Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| COX2 --- 5LOX | 4-[2-(3H-1lambda*4*-Benzo[b]thiophen-3-yl)-vinyl]-2,6-dimethyl-phenol | Drug Info |
| CAII --- CAI | (R)-4-((8S,10S,12S,14R,15R,17S)-10,13-Dimethyl-3,7,12-trioxo-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-pentanoic acid (3-sulfamoyl-phenyl)-amide | Drug Info |
| COX2 --- 5LOX | 2-Fluoro-6-methyl-4-(2-thiophen-2-yl-vinyl)-phenol | Drug Info |
| CAII --- CAI | 4-[3-Methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-(2E)-ylidenesulfamoyl]-benzoic acid 2-methoxy-ethyl ester | Drug Info |
| COX2 --- 5LOX | 3-(4-tert-Butylphenyl)-6-nitrobenzo[1.3.2]dithiazolium ylide 1,1-dioxide | Drug Info |
| CAII --- CAI | 4-(3,4,5-Trihydroxy-tetrahydro-pyran-2-ylamino)-benzenesulfonamide | Drug Info |
| CSrc --- CABL | 1-(2-chloro-2-(4-chlorophenyl)ethyl)-6-(methylthio)-N-phenethyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine | Drug Info |
| CAII --- CAI | N-(2-Fluorobenzyl)(4-sulphonamide phenyl)ethanamine | Drug Info |
| CSrc --- CABL | 1-(2-chloro-2-(4-fluorophenyl)ethyl)-6-(methylthio)-N-phenethyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine | Drug Info |
| CAII --- CAI | (S)-3-Hydroxy-3-phenyl-2-(4-sulfamoyl-benzoylamino)-propionic acid | Drug Info |
| CSrc --- CABL | N-(5-(benzylthio)-1,3,4-thiadiazol-2-yl)-4-chlorobenzamide | Drug Info |
| CAII --- CAI | 4-[4-(4-Methoxy-phenyl)-[1,2,3]triazol-1-yl]-benzenesulfonamide | Drug Info |
| CSrc --- CABL | N-(3-bromophenyl)-1-(2-chloro-2-phenylethyl)-6-(methylthio)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | Drug Info |
| CAII --- CAI | 1-[(2,3-Dichloro-4,6-disulfamoyl-phenylcarbamoyl)-methyl]-2,6-diethyl-4-phenyl-pyridinium; perchlorate | Drug Info |
| CSrc --- CABL | 9-(2,6-dimethylstyryl)-N-(4-(dimethylphosphoryl)phenyl)-2-isopropoxy-9H-purin-6-amine | Drug Info |
| CAII --- CAI | {{2-[2-(2-{Carboxymethyl-[(3-methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-2-ylidenecarbamoyl)-methyl]-amino}-ethoxy)-ethoxy]-ethyl}-[(3-methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-2-ylidenecarbamoyl)-methyl]-amino}-acetic acid; compound with Zn complex | Drug Info |
| CSrc --- Ckit | ethyl 4-(3-(2-aminoquinazolin-6-yl)-4-methyl-2-oxopyridin-1(2H)-yl)benzoate | Drug Info |
| CAII --- CAI | sodium trithiocarbonate | Drug Info |
| DHFR --- TYMS | N-[4-[(2-amino-6-methyl-3,4-dihydro-4-oxo-7H-pyrrolo-[2,3-d]pyrimidin-5-yl)thio]-2'fluorobenzoyl]L-glutamic acid | Drug Info |
| CAII --- CAI | Hydrochlorothiazide | Drug Info |
| DHFR --- TYMS | 2-{4-[(4-Hydroxy-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid | Drug Info |
| CAII --- CAI | N-(2-Diethylamino-ethyl)-3-(5-sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-benzamide | Drug Info |
| EGFR --- HER2 | (E)-3-(3,4-Dihydroxy-phenyl)-2-(2,4,6-trimethyl-benzoyl)-acrylonitrile | Drug Info |
| CAII --- CAI | 2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,9-Heptadecafluoro-nonanoic acid 2-sulfamoyl-benzothiazol-6-yl ester | Drug Info |
| EGFR3 --- Beta PDGFR | 4-(6,7-Dimethoxy-quinoxalin-2-ylamino)-cyclohexanol | Drug Info |
| CAII --- CAI | (Carboxymethyl-{[2-(4-sulfamoyl-phenyl)-ethylcarbamoyl]-methyl}-amino)-acetic acid | Drug Info |
| EGFR3 --- CSrc | (3-Chloro-phenyl)-[3-(3-nitro-phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]-amine | Drug Info |
| CAII --- CAI | 4-Methyl-5-(nonafluorobutane-1-sulfonylimino)-4,5-dihydro-[1,3,4]thiadiazole-2-sulfonic acid amide | Drug Info |
| EGFR3 --- HER2 | (E)-4-[3-Chloro-4-(3-fluorobenzyloxy)anilino]-6-[3-(3,4-dimethoxycinnamamido)phenoxy]pyrimidine | Drug Info |
| CAII --- CAI | N-(2-bromo-4-sulfamoylphenyl)-2-phenylacetamide | Drug Info |
| EGFR3 --- HER2 | N-[4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl]-2-propynamide | Drug Info |
| CAII --- CAI | 4-{3-[2-(1H-Imidazol-4-yl)-ethyl]-thioureido}-benzenesulfonamide | Drug Info |
| EGFR3 --- HER2 | (4-Benzyloxy-phenyl)-{6-[2-(2-methanesulfonyl-ethylamino)-thiazol-4-yl]-quinazolin-4-yl}-amine | Drug Info |
| CAII --- CAI | Ethyl-((4S,6S)-6-methyl-7,7-dioxo-2-sulfamoyl-4,5,6,7-tetrahydro-7lambda*6*-thieno[2,3-b]thiopyran-4-yl)-carbamic acid 2,3-bis-nitrooxy-propyl ester | Drug Info |
| EGFR3 --- HER2 | 4-Azetidin-1-yl-but-2-enoic acid [4-(4-benzyloxy-3-chloro-phenylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-amide | Drug Info |
| CAII --- CAI | 2,6-Dimethyl-4-phenyl-1-[2-(4-sulfamoyl-phenyl)-ethoxycarbonylmethyl]-pyridinium; perchlorate | Drug Info |
| EGFR3 --- HER2 | 2-(2-(4-Nitrobenzylidene)hydrazinyl)thiazol-4(5H)-one | Drug Info |
| CAII --- CAI | 2-Amino-N-[2-(4-sulfamoyl-phenyl)-ethyl]-acetamide | Drug Info |
| EGFR3 --- HER2 | 7-(4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ylthio)-N-hydroxyheptanamide | Drug Info |
| CAII --- CAI | 4-(2-(((1S)-7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methylsulfonamido)ethyl)benzene sulfonamide | Drug Info |
| EGFR3 --- HER2 | N-(4-(3-chloro-4-fluorophenylamino)-3-cyano-7-methoxyquinolin-6-yl)-4-(diethylamino)pent-2-enamide | Drug Info |
| CAII --- CAI | 1-(3,4-Dichloro-phenyl)-3-(5-mercapto-[1,3,4]thiadiazol-2-yl)-urea | Drug Info |
| CAII --- CAI | 2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,9-Heptadecafluoro-nonanoic acid (2-sulfamoyl-phenyl)-amide | Drug Info |
| CAII --- CAI | [(2-{2-[2-(Bis-carboxymethyl-amino)-ethoxy]-ethoxy}-ethyl)-(2-sulfamoyl-benzothiazol-6-yloxycarbonylmethyl)-amino]-acetic acid | Drug Info |
| CAII --- CAI | ((2-Hydroxy-phenyl)-{2-[(2-hydroxy-phenyl)-(4-sulfamoyl-benzyloxycarbonylmethyl)-amino]-ethyl}-amino)-acetic acid | Drug Info |
| CAII --- CAI | N,N-dialkylthio-carbonylsulfenylamino derivative | Drug Info |
| CAII --- CAI | 6-Pentafluorobenzenesulfonylamino-benzothiazole-2-sulfonic acid amide | Drug Info |
| CAII --- CAI | (S)-2-[3-(4-Sulfamoyl-phenyl)-thioureido]-succinamic acid methylcarbamoylmethyl with resin | Drug Info |
| CAII --- CAI | 6-(2-Sulfamoyl-benzothiazol-6-ylcarbamoyl)-pyridine-2-carboxylic acid | Drug Info |
| CAII --- CAIX | 4-(bis(4-methylpiperidin-1-yl)amino)-N-(4-sulfamoylphenyl)butanamide | Drug Info |
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