Target Information
Target General Infomation | |||||
---|---|---|---|---|---|
Target ID |
T88729
|
||||
Former ID |
TTDR00082
|
||||
Target Name |
Mitochondrial brown fat uncoupling protein 1
|
||||
Gene Name |
UCP1
|
||||
Synonyms |
Mitochondrial uncoupling protein 1; Thermogenin; UCP 1; UCP1
|
||||
Target Type |
Clinical Trial
|
||||
Disease | Obesity [ICD9: 278; ICD10: E66] | ||||
Function |
UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat.
|
||||
BioChemical Class |
Mitochondrial carrier
|
||||
UniProt ID | |||||
Sequence |
MGGLTASDVHPTLGVQLFSAGIAACLADVITFPLDTAKVRLQVQGECPTSSVIRYKGVLG
TITAVVKTEGRMKLYSGLPAGLQRQISSASLRIGLYDTVQEFLTAGKETAPSLGSKILAG LTTGGVAVFIGQPTEVVKVRLQAQSHLHGIKPRYTGTYNAYRIIATTEGLTGLWKGTTPN LMRSVIINCTELVTYDLMKEAFVKNNILADDVPCHLVSALIAGFCATAMSSPVDVVKTRF INSPPGQYKSVPNCAMKVFTNEGPTAFFKGLVPSFLRLGSWNVIMFVCFEQLKRELSKSR QTMDCAT |
||||
Drugs and Mode of Action | |||||
Pathways | |||||
References |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.