Target Information
| Target General Infomation | |||||
|---|---|---|---|---|---|
| Target ID |
T99740
|
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| Former ID |
TTDC00022
|
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| Target Name |
mRNA of Myb proto-oncogene protein
|
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| Gene Name |
MYB
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| Synonyms |
C-myb; MYB
|
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| Target Type |
Clinical Trial
|
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| Disease | Myeloid leukemia [ICD9: 208.9; ICD10: C92] | ||||
| BioChemical Class |
Target of antisense drug
|
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| Target Validation |
T99740
|
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| UniProt ID | |||||
| Sequence |
MARRPRHSIYSSDEDDEDFEMCDHDYDGLLPKSGKRHLGKTRWTREEDEKLKKLVEQNGT
DDWKVIANYLPNRTDVQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSVIAK HLKGRIGKQCRERWHNHLNPEVKKTSWTEEEDRIIYQAHKRLGNRWAEIAKLLPGRTDNA IKNHWNSTMRRKVEQEGYLQESSKASQPAVATSFQKNSHLMGFAQAPPTAQLPATGQPTV NNDYSYYHISEAQNVSSHVPYPVALHVNIVNVPQPAAAAIQRHYNDEDPEKEKRIKELEL LLMSTENELKGQQVLPTQNHTCSYPGWHSTTIADHTRPHGDSAPVSCLGEHHSTPSLPAD PGSLPEESASPARCMIVHQGTILDNVKNLLEFAETLQFIDSFLNTSSNHENSDLEMPSLT STPLIGHKLTVTTPFHRDQTVKTQKENTVFRTPAIKRSILESSPRTPTPFKHALAAQEIK YGPLKMLPQTPSHLVEDLQDVIKQESDESGIVAEFQENGPPLLKKIKQEVESPTDKSGNF FCSHHWEGDSLNTQLFTQTSPVADAPNILTSSVLMAPASEDEDNVLKAFTVPKNRSLASP LQPCSSTWEPASCGKMEEQMTSSSQARKYVNAFSARTLVM |
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| Drugs and Mode of Action | |||||
| Target Expression Profile (TEP) and Drug Resistance Mutation (DRM) | |||||
| TEP | EXP Info | ||||
| Pathways | |||||
| KEGG Pathway | PI3K-Akt signaling pathway | ||||
| HTLV-I infection | |||||
| NetPath Pathway | TCR Signaling Pathway | ||||
| IL2 Signaling Pathway | |||||
| Pathway Interaction Database | IL4-mediated signaling events | ||||
| IL2 signaling events mediated by PI3K | |||||
| AP-1 transcription factor network | |||||
| C-MYB transcription factor network | |||||
| Notch-mediated HES/HEY network | |||||
| Reactome | Factors involved in megakaryocyte development and platelet production | ||||
| WikiPathways | SIDS Susceptibility Pathways | ||||
| EV release from cardiac cells and their functional effects | |||||
| Hematopoietic Stem Cell Differentiation | |||||
| Neural Crest Differentiation | |||||
| miR-targeted genes in lymphocytes - TarBase | |||||
| Factors involved in megakaryocyte development and platelet production | |||||
| References | |||||
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