Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX6K1S
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| Drug Name |
2-((3,5-dichlorophenyl)(thiophen-2-yl)methylene)hydrazinecarbothioamide
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| Synonyms |
CHEMBL496424
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C12H9Cl2N3S2
|
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| Canonical SMILES |
NC(=S)N\\N=C(/c1cc(Cl)cc(Cl)c1)\\c2cccs2
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| InChI |
InChI=1S/C12H9Cl2N3S2/c13-8-4-7(5-9(14)6-8)11(16-17-12(15)18)10-2-1-3-19-10/h1-6H,(H3,15,17,18)/b16-11+
|
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| InChIKey |
GLGCLPLEIOLAJV-LFIBNONCSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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