Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXJJ0L
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| Drug Name |
2-(4-Bromo-thiophen-3-ylamino)-4-methyl-pentanoic acid cyanomethyl-amide
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| Synonyms |
CHEMBL365007
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C12H16BrN3OS
|
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| Canonical SMILES |
CC(C)C[C@H](Nc1cscc1Br)C(=O)NCC#N
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| InChI |
InChI=1S/C12H16BrN3OS/c1-8(2)5-10(12(17)15-4-3-14)16-11-7-18-6-9(11)13/h6-8,10,16H,4-5H2,1-2H3,(H,15,17)/t10-/m0/s1
|
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| InChIKey |
KGJLXDHUTKATFA-JTQLQIEISA-N
|
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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