Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX8XQX
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| Drug Name |
4-(3-methoxyphenyl)-2-methyl-7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tetrahydro-2,6-naphthyridine
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| Synonyms |
CHEMBL241705
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| Indication | Discovery agent | Investigative | [1] | ||
| Formula |
C24H33N3O2
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| Canonical SMILES |
COc1cccc(c1)C2CN(C)Cc3cc(OCCCN4CCCCC4)ncc23
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| InChI |
InChI=1S/C24H33N3O2/c1-26-17-20-15-24(29-13-7-12-27-10-4-3-5-11-27)25-16-22(20)23(18-26)19-8-6-9-21(14-19)28-2/h6,8-9,14-16,23H,3-5,7,10-13,17-18H2,1-2H3
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| InChIKey |
FINNTOGAVZWNGL-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Histamine H3 receptor | Target Info | [1] | ||
| Sodium-dependent serotonin transporter | Target Info | [1] | |||
| KEGG Pathway | Neuroactive ligand-receptor interactionhsa04726:Serotonergic synapse | ||||
| NetPath Pathway | TCR Signaling Pathway | ||||
| PANTHER Pathway | 5HT1 type receptor mediated signaling pathway | ||||
| 5HT2 type receptor mediated signaling pathway | |||||
| 5HT3 type receptor mediated signaling pathway | |||||
| 5HT4 type receptor mediated signaling pathway | |||||
| Reactome | Histamine receptors | ||||
| G alpha (i) signalling events | |||||
| WikiPathways | Monoamine Transport | ||||
| GPCRs, Class A Rhodopsin-like | |||||
| GPCR ligand binding | |||||
| GPCR downstream signalingWP727:Monoamine Transport | |||||
| SIDS Susceptibility Pathways | |||||
| NRF2 pathway | |||||
| Synaptic Vesicle Pathway | |||||
| Serotonin Transporter Activity | |||||
| References | |||||
| REF 1 | URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017 | ||||
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