Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXUY5W
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| Drug Name |
4'-[1-(2-Methoxy-ethyl)-piperidin-4-yloxy]-biphenyl-4-carboxylic acid [1-(cyanomethyl-carbamoyl)-cyclohexyl]-amide
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| Synonyms |
CHEMBL199214
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C30H38N4O4
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| Canonical SMILES |
COCCN1CCC(CC1)Oc2ccc(cc2)c3ccc(cc3)C(=O)NC4(CCCCC4)C(=O)NCC#N
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| InChI |
InChI=1S/C30H38N4O4/c1-37-22-21-34-19-13-27(14-20-34)38-26-11-9-24(10-12-26)23-5-7-25(8-6-23)28(35)33-30(15-3-2-4-16-30)29(36)32-18-17-31/h5-12,27H,2-4,13-16,18-22H2,1H3,(H,32,36)(H,33,35)
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| InChIKey |
WNPXWVCMSQKVNE-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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