Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXV9PS
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| Drug Name |
4'-[Methyl-(1-methyl-pyrrolidin-3-yl)-amino]-biphenyl-4-carboxylic acid [1-(cyanomethyl-carbamoyl)-cyclohexyl]-amide
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| Synonyms |
CHEMBL381190
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C28H35N5O2
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| Canonical SMILES |
CN(C1CCN(C)C1)c2ccc(cc2)c3ccc(cc3)C(=O)NC4(CCCCC4)C(=O)NCC#N
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| InChI |
InChI=1S/C28H35N5O2/c1-32-19-14-25(20-32)33(2)24-12-10-22(11-13-24)21-6-8-23(9-7-21)26(34)31-28(15-4-3-5-16-28)27(35)30-18-17-29/h6-13,25H,3-5,14-16,18-20H2,1-2H3,(H,30,35)(H,31,34)
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| InChIKey |
BDSZVNUUBYFZNJ-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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