Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX3CUM
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| Drug Name |
N-(1-((cyanomethyl)carbamoyl)cyclohexyl)-5-bromothiophene-2-carboxamide
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| Synonyms |
CHEMBL200167
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C14H16BrN3O2S
|
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| Canonical SMILES |
Brc1ccc(s1)C(=O)NC2(CCCCC2)C(=O)NCC#N
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| InChI |
InChI=1S/C14H16BrN3O2S/c15-11-5-4-10(21-11)12(19)18-14(6-2-1-3-7-14)13(20)17-9-8-16/h4-5H,1-3,6-7,9H2,(H,17,20)(H,18,19)
|
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| InChIKey |
MYQWFADAHVCPFY-UHFFFAOYSA-N
|
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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