Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX2VL1
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| Drug Name |
N-(cyanomethyl)-3-(3,5-dimethylphenyl)-2-(2,2-diphenylacetamido)propanamide
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| Synonyms |
CHEMBL477531
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C27H27N3O2
|
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| Canonical SMILES |
Cc1cc(C)cc(CC(NC(=O)C(c2ccccc2)c3ccccc3)C(=O)NCC#N)c1
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| InChI |
InChI=1S/C27H27N3O2/c1-19-15-20(2)17-21(16-19)18-24(26(31)29-14-13-28)30-27(32)25(22-9-5-3-6-10-22)23-11-7-4-8-12-23/h3-12,15-17,24-25H,14,18H2,1-2H3,(H,29,31)(H,30,32)
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| InChIKey |
UHSPVUASELRRIQ-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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