TTD | Drug: D07ROK

Drug General Information
Drug ID	D07ROK
Former ID	DNC007815
Drug Name	N-(3-(1H-indol-4-yloxy)propyl)cyclopentanamine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[529018]
Structure		Download 2D MOL 3D MOL
Formula	C16H22N2O
Canonical SMILES	C1CCC(C1)NCCCOC2=CC=CC3=C2C=CN3
InChI	1S/C16H22N2O/c1-2-6-13(5-1)17-10-4-12-19-16-8-3-7-15-14(16)9-11-18-15/h3,7-9,11,13,17-18H,1-2,4-6,10,12H2
InChIKey	IYOLOIDWTZSJFT-UHFFFAOYSA-N
PubChem Compound ID	44433248
Target and Pathway
Target(s)	5-hydroxytryptamine 1A receptor	Target Info	Inhibitor	[529018]
KEGG Pathway	cAMP signaling pathway
	Neuroactive ligand-receptor interaction
	Serotonergic synapse
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PANTHER Pathway	5HT1 type receptor mediated signaling pathway
Reactome	Serotonin receptors
Reactome	G alpha (i) signalling events
WikiPathways	Serotonin HTR1 Group and FOS Pathway
	SIDS Susceptibility Pathways
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 529018	Bioorg Med Chem Lett. 2007 Oct 15;17(20):5600-4. Epub 2007 Aug 22.Indoloxypropanolamine analogues as 5-HT(1A) receptor antagonists.
Ref 529018	Bioorg Med Chem Lett. 2007 Oct 15;17(20):5600-4. Epub 2007 Aug 22.Indoloxypropanolamine analogues as 5-HT(1A) receptor antagonists.

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Drug Information