Drug General Information
Drug ID
D08UQS
Former ID
DCL000879
Drug Name
MEM-1003
Drug Type
Small molecular drug
Indication Bipolar disorder [ICD9: 296.0, 296.1, 296.4, 296.5, 296.6, 296.7, 296.8, 300; ICD10:F31, F40-F42] Phase 2a [536295]
Dementia [ICD9: 290-294; ICD10:F01-F07] Phase 2 [528140]
Company
Bayer
Structure
Download
2D MOL

3D MOL

Formula
C20H21FKN6O5
Canonical SMILES
CC1=NN=C(O1)C(=O)NC(C)(C)C2=NC(=C(C(=O)N2C)O)C(=O)NCC3=<br />CC=C(C=C3)F.[K]
InChI
1S/C20H21FN6O5.K/c1-10-25-26-17(32-10)16(30)24-20(2,3)19-23-13(14(28)18(31)27(19)4)15(29)22-9-11-5-7-12(21)8-6-11;/h5-8,28H,9H2,1-4H3,(H,22,29)(H,24,30);
InChIKey
NLDVPINGTPMESH-UHFFFAOYSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) L-type calcium channel Target Info Modulator [528140]
References
Ref 528140Efficacy of MEM 1003, a novel calcium channel blocker, in delay and trace eyeblink conditioning in older rabbits. Neurobiol Aging. 2007 May;28(5):766-73. Epub 2006 Apr 18.
Ref 536295Emerging drugs for bipolar disorder. Expert Opin Emerg Drugs. 2006 Nov;11(4):621-34.
Ref 528140Efficacy of MEM 1003, a novel calcium channel blocker, in delay and trace eyeblink conditioning in older rabbits. Neurobiol Aging. 2007 May;28(5):766-73. Epub 2006 Apr 18.

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