Drug General Information
Drug ID	D0SX4K
Former ID	DNC000742
Drug Name	HR325
Drug Type	Small molecular drug
Indication	Rheumatoid arthritis [ICD9: 710-719, 714; ICD10:M05-M06]		Discontinued in Phase 2	[545844]
Structure		Download 2D MOL 3D MOL
Formula	C15H13F3N2O2
PubChem Compound ID	5487544
Target and Pathway
Target(s)	Dihydroorotate dehydrogenase	Target Info	Modulator
KEGG Pathway	Pyrimidine metabolism
	Metabolic pathways
PANTHER Pathway	De novo pyrimidine ribonucleotides biosythesis
PathWhiz Pathway	Pyrimidine Metabolism
Reactome	Pyrimidine biosynthesis
WikiPathways	Metabolism of nucleotides
References
Ref 545844	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005016)

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