Drug Information
Drug General Information | |||||
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Drug ID |
D0L1BS
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Former ID |
DIB007298
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Drug Name |
PF-454583
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Synonyms |
PF-454583; PF-4926965; Opioid receptor-like 1 (ORL1) antagonists (Alzheimer's disease), Pfizer
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Drug Type |
Small molecular drug
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Indication | Major depressive disorder [ICD9: 296.2, 296.3, 710.0; ICD10:F32, F33, M32] | Investigative | [543766] | ||
Company |
Pfizer Inc
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Structure |
Download2D MOL |
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Formula |
C21H26ClFN4O2
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Canonical SMILES |
CN(C)C(=O)C(CN1CCC2(CC1)C3=C(CO2)C=CC(=C3)F)CN4C=C(C=N4<br />)Cl
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InChI |
1S/C21H26ClFN4O2/c1-25(2)20(28)16(12-27-13-17(22)10-24-27)11-26-7-5-21(6-8-26)19-9-18(23)4-3-15(19)14-29-21/h3-4,9-10,13,16H,5-8,11-12,14H2,1-2H3
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InChIKey |
BVXVLXUGXQOMEP-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Nociceptin receptor | Target Info | Antagonist | [543766] | |
KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
References |
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