Target Information

Target General Infomation
Target ID
T52617
Former ID
TTDR01245
Target Name
3-oxoacyl-[acyl-carrier-protein] synthase 1
Gene Name
kasA
Synonyms
Beta-ketoacyl-ACP synthase 1; KAS 1; kasA
Target Type
Research
Function
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-acp (by similarity).
BioChemical Class
Acyltransferase
UniProt ID
P9WQD9
EC Number
EC 2.3.1.41
Sequence
MSQPSTANGGFPSVVVTAVTATTSISPDIESTWKGLLAGESGIHALEDEFVTKWDLAVKI
GGHLKDPVDSHMGRLDMRRMSYVQRMGKLLGGQLWESAGSPEVDPDRFAVVVGTGLGGAE
RIVESYDLMNAGGPRKVSPLAVQMIMPNGAAAVIGLQLGARAGVMTPVSACSSGSEAIAH
AWRQIVMGDADVAVCGGVEGPIEALPIAAFSMMRAMSTRNDEPERASRPFDKDRDGFVFG
EAGALMLIETEEHAKARGAKPLARLLGAGITSDAFHMVAPAADGVRAGRAMTRSLELAGL
SPADIDHVNAHGTATPIGDAAEANAIRVAGCDQAAVYAPKSALGHSIGAVGALESVLTVL
TLRDGVIPPTLNYETPDPEIDLDVVAGEPRYGDYRYAVNNSFGFGGHNVALAFGRY
Inhibitor 2-PHENYLAMINO-4-METHYL-5-ACETYL THIAZOLE Drug Info [551374]
Caprylic acid Drug Info [551385]
Decanoic Acid Drug Info [551393]
Lauric Acid Drug Info [551393]
Target Expression Profile (TEP) and Drug Resistance Mutation (DRM)
DRM DRM Info
References
Ref 551374The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
Ref 551385Characterization of ochratoxin A transport by human organic anion transporters. Life Sci. 2001 Sep 21;69(18):2123-35.
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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