Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D00DIF
|
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| Former ID |
DIB019680
|
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| Drug Name |
CyPPA
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C16H23N5
|
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| InChI |
InChI=1S/C16H23N5/c1-11-10-15(18-14-7-5-4-6-8-14)19-16(17-11)21-13(3)9-12(2)20-21/h9-10,14H,4-8H2,1-3H3,(H,17,18,19)
|
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| InChIKey |
USEMRPYUFJNFQN-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
1159006, 4771447, 9195752, 25665763, 44509793, 46497387, 49699829, 50526756, 88258261, 90340684, 103647907, 104118715, 110085298, 121298541, 121361699, 135650151, 135698352, 162248103, 163133782, 163375797, 163563919, 163564661, 163838085, 166716506, 170558751, 175612513, 223532337, 229268723, 248514668, 249827909, 250201140, 252059710, 252156899, 252229796, 252425571, 252552971
|
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| Target and Pathway | |||||
| Target(s) | KCa2.2 | Target Info | Activator | [2] | |
| KCa2.3 | Target Info | Activator | [2] | ||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2323). | ||||
| REF 2 | Selective positive modulation of the SK3 and SK2 subtypes of small conductance Ca2+-activated K+ channels. Br J Pharmacol. 2007 Jul;151(5):655-65. Epub 2007 May 8. | ||||
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