Drug Information
Drug General Information | |||||
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Drug ID |
D00ETS
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Former ID |
DAP000688
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Drug Name |
Hexobarbital
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Synonyms |
Barbidorm; Citodon; Citopan; Cyclonal; Cyclopan; Dorico; Enhexymal; Enhexymalum; Esobarbitale; Evipal; Evipan; Hexabarbital;Hexobarbitalum; Hexobarbitone; Hexobarbitonum; Methexenyl; Methylhexabarbital; Methylhexabital; Narcosan; Noctivane; Sombucaps; Sombulex; Somnalert; Esobarbitale [DCIT]; Esobarbitale [Italian]; Hexanastab oral; Sodium hexobarbital; Citopan (TN); Evipan (TN); Hexenal (barbiturate); Hexobarbital (VAN); Hexobarbital [INN:JAN]; Hexobarbitalum [INN-Latin]; Hexobarbital (JAN/INN); N-Methyl-5-cyclohexenyl-5-methylbarbituric acid; (+-)-Hexobarbital; 1,5-Dimethyl-5-(1-cyclohexenyl)barbituric acid; 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(1-cyclohexen-1-yl)-1,5-dimethyl; 5-(1-CYCLOHEXEN-1-YL)-1,5-DIMETHYLBARBITURIC ACID; 5-(1-Cyclohexen-1-yl)-1,5-dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione; 5-(1-Cyclohexenyl)-1,5-dimethylbarbituric acid; 5-(1-Cyclohexenyl-1)-1-methyl-5-methylbarbituric acid; 5-(cyclohex-1-en-1-yl)-1,5-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione; 5-(cyclohexen-1-yl)-1,5-dimethyl-1,3-diazinane-2,4,6-trione; 5-(delta-1,2-Cyclohexenyl)-5-methyl-N-methyl-barbitursaeure [German]; 5-(delta-1,2-cyclohexenyl)-5-methyl-N-methyl-barbitursaeure; 5-(delta.-1,2-cyclohexenyl)-5-methyl-N-methyl-barbitursaeure; 5-cyclohex-1-en-1-yl-1,5-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione; 5-cyclohex-1-en-1-yl-2-hydroxy-1,5-dimethylpyrimidine-4,6(1H,5H)-dione
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Drug Type |
Small molecular drug
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Indication | Anesthesia [ICD9: 338; ICD10:R20.0] | Approved | [550698] | ||
Therapeutic Class |
Hypnotics and Sedatives
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Structure |
Download2D MOL |
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Formula |
C12H16N2O3
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Canonical SMILES |
CC1(C(=O)NC(=O)N(C1=O)C)C2=CCCCC2
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InChI |
1S/C12H16N2O3/c1-12(8-6-4-3-5-7-8)9(15)13-11(17)14(2)10(12)16/h6H,3-5,7H2,1-2H3,(H,13,15,17)
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InChIKey |
UYXAWHWODHRRMR-UHFFFAOYSA-N
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CAS Number |
CAS 56-29-1
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PubChem Compound ID | |||||
PubChem Substance ID |
13888, 114792, 4911070, 7848134, 8147019, 8152276, 10527424, 15415683, 24895418, 26754503, 29215369, 29222734, 46508777, 47194291, 47959959, 48416081, 49873997, 57309846, 57321894, 57654225, 79698506, 92714691, 103165870, 104304001, 104903183, 117838626, 118856010, 124813353, 124892192, 125309499, 125488787, 126623945, 129440427, 134337977, 134972602, 135194968, 135300355, 137101291, 139408774, 144205214, 144205215, 144236491, 160964645, 163050404, 164815041, 170250749, 170465860, 176267018, 179225803, 179296095
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ChEBI ID |
ChEBI:5706
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SuperDrug ATC ID |
N01AF02; N05CA16
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SuperDrug CAS ID |
cas=000056291
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Target and Pathway | |||||
Target(s) | Gamma-aminobutyric acid receptor subunit alpha-1 | Target Info | Antagonist | [536555], [537688] | |
References | |||||
Ref 536555 | DrugBank: a knowledgebase for drugs, drug actions and drug targets. Nucleic Acids Res. 2008 Jan;36(Database issue):D901-6. Epub 2007 Nov 29. | ||||
Ref 537688 | Effect of barbiturates on polyphosphoinositide biosynthesis and protein kinase C activity in synaptosomes. Neuropharmacology. 1989 Dec;28(12):1317-23. |
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