Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D01BUT
|
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| Former ID |
DIB007389
|
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| Drug Name |
LXT-101
|
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| Synonyms |
DepoLXT-101; GnRH antagonist (sustained release, prostate cancer), Beijing Institute of Pharmacology and Toxicology
|
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| Indication | Prostate cancer [ICD9: 185; ICD10:C61] | Investigative | [1] | ||
| Company |
Beijing Institute of Pharmacology and Toxicology
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| Structure |
|
Download2D MOL |
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| Target and Pathway | |||||
| Target(s) | Gonadotropin-releasing hormone receptor | Target Info | Antagonist | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| GnRH signaling pathway | |||||
| NetPath Pathway | IL1 Signaling Pathway | ||||
| IL2 Signaling Pathway | |||||
| PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | ||||
| Reactome | Hormone ligand-binding receptors | ||||
| G alpha (q) signalling events | |||||
| WikiPathways | Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| Peptide GPCRs | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| GPCRs, Other | |||||
| References | |||||
| REF 1 | Regul Pept. 2006 Sep 11;136(1-3):122-9. Epub 2006 Jul 10.In vivo characterization of a novel GnRH (gonadotropin-releasing hormone) antagonist, LXT-101, in normal male rats. | ||||
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