Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D01WJM
|
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| Former ID |
DIB016677
|
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| Drug Name |
D-26344
|
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| Indication | Cancer [ICD9: 140-229; ICD10:C00-C96] | Terminated | [1] | ||
| Company |
ASTA Medica AG
|
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| Structure |
|
Download2D MOL |
|||
| Canonical SMILES |
N1(C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@@H](NC<br />(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](NC(=O)[C@H](NC(=O)C)<br />Cc2cc3c(cc2)cccc3)Cc2ccc(Cl)cc2)Cc2cnccc2)CO)Cc2ccc(cc2<br />)O)CCCCNC(=O)CCC(=O)Nc2ccc(C(=N)N)cc2)CC(C)C)CCCNC(=N)N<br />)[C@H](C(=O)N[C@@H](C(=O)N)C)CCC1
|
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| CAS Number |
CAS 191611-37-7
|
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| Target and Pathway | |||||
| Target(s) | Gonadotropin-releasing hormone receptor | Target Info | Inhibitor | [2] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| GnRH signaling pathway | |||||
| NetPath Pathway | IL1 Signaling Pathway | ||||
| IL2 Signaling Pathway | |||||
| PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | ||||
| Reactome | Hormone ligand-binding receptors | ||||
| G alpha (q) signalling events | |||||
| WikiPathways | Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| Peptide GPCRs | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| GPCRs, Other | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800013297) | ||||
| REF 2 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003256) | ||||
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