Drug Information

Drug General Information
Drug ID
D02UQU
Former ID
DIB012881
Drug Name
ABS-301
Synonyms
ABS-301; ABS-302; ABS-303; ABS-304; Tacrine analogs, ABS
Indication Alzheimer disease [ICD9: 331; ICD10:G30] Terminated [546251]
Company
American Biogenetic Sciences Inc
Target and Pathway
Target(s) Acetylcholinesterase Target Info Modulator [534501]
KEGG Pathway Glycerophospholipid metabolism
Cholinergic synapse
PANTHER Pathway Muscarinic acetylcholine receptor 1 and 3 signaling pathway
Muscarinic acetylcholine receptor 2 and 4 signaling pathway
Nicotinic acetylcholine receptor signaling pathway
Pathway Interaction Database ATF-2 transcription factor network
PathWhiz Pathway Phospholipid Biosynthesis
WikiPathways Monoamine Transport
Biogenic Amine Synthesis
Acetylcholine Synthesis
Integrated Pancreatic Cancer Pathway
References
Ref 546251Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007119)
Ref 534501Novel tacrine analogues for potential use against Alzheimer's disease: potent and selective acetylcholinesterase inhibitors and 5-HT uptake inhibitors. J Med Chem. 1997 Oct 24;40(22):3516-23.

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