Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D03LLM
|
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| Former ID |
DIB020959
|
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| Drug Name |
SLG
|
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| Synonyms |
1-stearoyl-2-linoleoyl-sn-glycerol
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C39H72O5
|
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| InChI |
InChI=1S/C39H72O5/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-38(41)43-36-37(35-40)44-39(42)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h12,14,18,20,37,40H,3-11,13,15-17,19,21-36H2,1-2H3/b14-12-,20-18-/t37-/m0/s1
|
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| InChIKey |
AJMZUFBKADIAKC-SKTOPKGQSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Short transient receptor potential channel 6 | Target Info | Activator | [2] | |
| PANTHER Pathway | Alzheimer disease-presenilin pathway | ||||
| Pathway Interaction Database | Endothelins | ||||
| Nephrin/Neph1 signaling in the kidney podocyte | |||||
| EPO signaling pathway | |||||
| PAR1-mediated thrombin signaling events | |||||
| Reactome | Effects of PIP2 hydrolysis | ||||
| TRP channels | |||||
| Role of second messengers in netrin-1 signaling | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| Platelet homeostasis | |||||
| Netrin-1 signaling | |||||
| GPCR downstream signaling | |||||
| Effects of PIP2 hydrolysis | |||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2442). | ||||
| REF 2 | Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol. Nature. 1999 Jan 21;397(6716):259-63. | ||||
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