Drug Information
Drug General Information | |||||
---|---|---|---|---|---|
Drug ID |
D03PEA
|
||||
Former ID |
DIB020528
|
||||
Drug Name |
NF546
|
||||
Synonyms |
NF-546
|
||||
Drug Type |
Small molecular drug
|
||||
Indication | Discovery agent | Investigative | [540646] | ||
Structure |
Download2D MOL |
||||
Formula |
C47H44N6Na4O17P4
|
||||
InChI |
InChI=1S/C47H48N6O17P4.4Na/c1-27-9-13-33(45(56)50-39-15-11-29(23-71(59,60)61)17-35(39)25-73(65,66)67)21-41(27)52-43(54)31-5-3-7-37(19-31)48-47(58)49-38-8-4-6-32(20-38)44(55)53-42-22-34(14-10-28(42)2)46(57)51-40-16-12-30(24-72(62,63)64)18-36(40)26-74(68,69)70;;;;/h3-22H,23-26H2,1-2H3,(H,50,56)(H,51,57)(H,52,54)(H,53,55)(H2,48,49,58)(H2,59,60,61)(H2,62,63,64)(H2,65,66,67)(H2,68,69,70);;;;/q;4*+1/p-4
|
||||
InChIKey |
GSMUPMANKNAMAS-UHFFFAOYSA-J
|
||||
PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | P2Y11 receptor | Target Info | Agonist | [530440] | |
References | |||||
Ref 530440 | NF546 [4,4'-(carbonylbis(imino-3,1-phenylene-carbonylimino-3,1-(4-methyl-phenylene)-carbonylimino))-bis(1,3-xylene-alpha,alpha'-diphosphonic acid) tetrasodium salt] is a non-nucleotide P2Y11 agonist and stimulates release of interleukin-8 from human monocyte-derived dendritic cells. J Pharmacol Exp Ther. 2010 Jan;332(1):238-47. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.