Drug General Information
Drug ID	D04LHJ
Drug Name	Methscopolamine Bromide
Synonyms	Methscopolamine Bromide; Pamine; Pamine Forte
Drug Type	Small molecular drug
Indication	Postoperative nausea and vomiting [ICD10:R11]		Approved	[551871]
Company	Private Formulations Inc
Structure		Download 2D MOL
Formula	C18H24BrNO4
PubChem Compound ID	9072
Target and Pathway
Target(s)	Muscarinic acetylcholine receptor M3	Target Info	Modulator
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Cholinergic synapse
	Regulation of actin cytoskeleton
	Insulin secretion
	Salivary secretion
	Gastric acid secretion
	Pancreatic secretion
PANTHER Pathway	Alzheimer disease-amyloid secretase pathway
	Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
	Muscarinic acetylcholine receptor 1 and 3 signaling pathway
PathWhiz Pathway	Gastric Acid Production
Reactome	Muscarinic acetylcholine receptors
	Acetylcholine regulates insulin secretion
	G alpha (q) signalling events
WikiPathways	Monoamine GPCRs
	Calcium Regulation in the Cardiac Cell
	Regulation of Actin Cytoskeleton
	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Integration of energy metabolism
	GPCR ligand binding
	GPCR downstream signaling
	GPCRs, Other
References
Ref 551871	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015

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