Drug General Information
Drug ID	D05EEV
Drug Name	DAU-5750
Synonyms	DAU-5750
Drug Type	Small molecular drug
Indication	Unspecified		Investigative	[1560114]
Structure		Download 2D MOL 3D MOL
Formula	C19H24N2O3
PubChem Compound ID	190973
Target and Pathway
Target(s)	Muscarinic acetylcholine receptor M1	Target Info	Modulator
	Muscarinic acetylcholine receptor M3	Target Info	Modulator
KEGG Pathway	Calcium signaling pathway
	cAMP signaling pathway
	Neuroactive ligand-receptor interaction
	PI3K-Akt signaling pathway
	Cholinergic synapse
	Regulation of actin cytoskeletonhsa04020:Calcium signaling pathway
	Regulation of actin cytoskeleton
	Insulin secretion
	Salivary secretion
	Gastric acid secretion
	Pancreatic secretion
PANTHER Pathway	Alzheimer disease-amyloid secretase pathway
	Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
	Muscarinic acetylcholine receptor 1 and 3 signaling pathwayP00003:Alzheimer disease-amyloid secretase pathway
	Muscarinic acetylcholine receptor 1 and 3 signaling pathway
PathWhiz Pathway	Gastric Acid Production
Reactome	Muscarinic acetylcholine receptors
	G alpha (q) signalling eventsR-HSA-390648:Muscarinic acetylcholine receptors
	Acetylcholine regulates insulin secretion
	G alpha (q) signalling events
WikiPathways	Monoamine GPCRs
	Calcium Regulation in the Cardiac Cell
	Regulation of Actin Cytoskeleton
	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Secretion of Hydrochloric Acid in Parietal Cells
	GPCR ligand binding
	GPCR downstream signalingWP58:Monoamine GPCRs
	Integration of energy metabolism
	GPCR downstream signaling
	GPCRs, Other
References
Ref 1560114	Synthesis, absolute configuration, conformational analysis and binding affinity properties of enantiomeric forms of DAU 5750, a novel M1-M3 muscarinic receptor antagonist.

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