Drug Information
Drug General Information | |||||
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Drug ID |
D05ZHQ
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Former ID |
DIB019807
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Drug Name |
EHNA
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Synonyms |
erythro-9-(2-hydroxy-3-nonyl)adenine hydrochloride
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [468240] | ||
Structure |
Download2D MOL |
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Formula |
C14H24ClN5O
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InChI |
InChI=1S/C14H23N5O.ClH/c1-3-4-5-6-7-11(10(2)20)19-9-18-12-13(15)16-8-17-14(12)19;/h8-11,20H,3-7H2,1-2H3,(H2,15,16,17);1H/t10-,11+;/m1./s1
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InChIKey |
VVDXNJRUNJMYOZ-DHXVBOOMSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | CGMP-dependent3',5'-cyclic phosphodiesterase | Target Info | Inhibitor | [534171] | |
Adenosine deaminase | Target Info | Inhibitor | [534055] | ||
PANTHER Pathway | Adenine and hypoxanthine salvage pathway | ||||
PathWhiz Pathway | Purine Metabolism | ||||
WikiPathways | Metabolism of nucleotides | ||||
References | |||||
Ref 534055 | Tight-binding inhibitors--IV. Inhibition of adenosine deaminases by various inhibitors. Biochem Pharmacol. 1977 Mar 1;26(5):359-67. | ||||
Ref 534171 | Rapid regulation of PDE-2 and PDE-4 cyclic AMP phosphodiesterase activity following ligation of the T cell antigen receptor on thymocytes: analysis using the selective inhibitors erythro-9-(2-hydroxy-3-nonyl)-adenine (EHNA) and rolipram. Cell Signal. 1996 Feb;8(2):97-110. |
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