Drug Information
Drug General Information | |||||
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Drug ID |
D06IRE
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Former ID |
DIB021085
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Drug Name |
trichloroethanol
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [539444] | ||
Structure |
Download2D MOL |
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Formula |
C2H3Cl3O
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InChI |
InChI=1S/C2H3Cl3O/c3-2(4,5)1-6/h6H,1H2
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InChIKey |
KPWDGTGXUYRARH-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID |
9693, 111467, 588139, 3134731, 7544284, 8144399, 8155783, 10504520, 12157173, 14709318, 15170878, 24900284, 29226971, 30952970, 33677449, 46394402, 48415142, 49968122, 57324883, 57389600, 74778195, 85090041, 87226434, 87576514, 88822997, 93617816, 103341628, 104317345, 113635236, 117618557, 125362849, 126546633, 126687820, 127280530, 127280531, 127280532, 127838658, 128131370, 128417629, 134974720, 135651278, 137004033, 142343713, 144087425, 162075472, 162124593, 162303546, 162757963, 163411210, 163849184
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Target and Pathway | |||||
Target(s) | 5-HT3AB | Target Info | Modulator (allosteric modulator) | [527834] | |
5-hydroxytryptamine receptor 3A | Target Info | Modulator (allosteric modulator) | [529227] | ||
KEGG Pathway | Serotonergic synapse | ||||
NetPath Pathway | IL2 Signaling Pathway | ||||
PANTHER Pathway | 5HT3 type receptor mediated signaling pathway | ||||
Reactome | Ligand-gated ion channel transport | ||||
WikiPathways | SIDS Susceptibility Pathways | ||||
Iron uptake and transport | |||||
References | |||||
Ref 527834 | Co-expression of the 5-HT(3B) subunit with the 5-HT(3A) receptor reduces alcohol sensitivity. Brain Res Mol Brain Res. 2005 Dec 14;142(2):146-50. Epub 2005 Oct 28. | ||||
Ref 529227 | Arginine 246 of the pretransmembrane domain 1 region alters 2,2,2-trichloroethanol action in the 5-hydroxytryptamine3A receptor. J Pharmacol Exp Ther. 2008 Mar;324(3):1011-8. Epub 2007 Dec 19. |
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