Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D06PII
|
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| Former ID |
DNC003384
|
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| Drug Name |
SULTHIAME
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Phase 3 | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C10H14N2O4S2
|
||||
| Canonical SMILES |
C1CCS(=O)(=O)N(C1)C2=CC=C(C=C2)S(=O)(=O)N
|
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| InChI |
1S/C10H14N2O4S2/c11-18(15,16)10-5-3-9(4-6-10)12-7-1-2-8-17(12,13)14/h3-6H,1-2,7-8H2,(H2,11,15,16)
|
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| InChIKey |
HMHVCUVYZFYAJI-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
5634029, 7848849, 8153291, 10529914, 14800055, 26737235, 29224408, 47216923, 48416585, 49881665, 53812969, 57298709, 57322733, 75255724, 99444800, 103304450, 104309002, 126666638, 128081403, 134224369, 134971035, 137010329, 143201330, 160969377, 163057234, 164765183, 170465788, 179226116, 198967283, 223366865, 223675966, 226424350, 250113307
|
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| SuperDrug ATC ID |
N03AX03
|
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| Target and Pathway | |||||
| Target(s) | Carbonic anhydrase II | Target Info | Inhibitor | [2] | |
| KEGG Pathway | Nitrogen metabolism | ||||
| Proximal tubule bicarbonate reclamation | |||||
| Collecting duct acid secretion | |||||
| Gastric acid secretion | |||||
| Pancreatic secretion | |||||
| Bile secretion | |||||
| NetPath Pathway | IL4 Signaling Pathway | ||||
| EGFR1 Signaling Pathway | |||||
| Reactome | Erythrocytes take up carbon dioxide and release oxygen | ||||
| Erythrocytes take up oxygen and release carbon dioxide | |||||
| Reversible hydration of carbon dioxide | |||||
| WikiPathways | Reversible Hydration of Carbon Dioxide | ||||
| Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes | |||||
| Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes | |||||
| References | |||||
| REF 1 | ClinicalTrials.gov (NCT00471744) HEAD-Study Optimizing the Treatment of Children With BECTS. U.S. National Institutes of Health. | ||||
| REF 2 | The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. | ||||
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