Drug Information
Drug General Information | |||||
---|---|---|---|---|---|
Drug ID |
D08UMH
|
||||
Former ID |
DAP000680
|
||||
Drug Name |
Methylphenobarbital
|
||||
Synonyms |
Enfenemal; Enphenemal; Enphenemalum; Mebaral; Meberal; Mebroin; Mephobarbital; Mephobarbitone; Mephytal; Methylphenobarbitalum; Methylphenobarbitone; Methylphenobarbitonum; Methylphenolbarbital; Metilfenobarbital; Metilfenobarbitale; Metylfenemal; Metyna; Morbusan; Phemetone; Phemiton; Phemitone; Phenmiton; Prominal; Prominaletten; Prominalum; Mephobarbital [JAN]; Methyl phenobarbitone; Methylphenylbarbituric acid; Metilfenobarbitale [DCIT]; Sanofi Brand of Mephobarbital; Sanofi Synthelabo Brand of Mephobarbital; Isonal (roussel); Mebaral (TN); Menta-Bal; Methyl-calminal; Methylphenobarbital (INN); Methylphenobarbitalum [INN-Latin]; Metilfenobarbital [INN-Spanish]; N-Ethylmethylphenylbarbituric acid; N-Methylethylphenylbarbituric acid; N-Methylphenobarbital; N-Methylphenolbarbitol; Mephobarbital (JAN/USP); N-Methyl-5-phenyl-5-ethylbarbital; 1-Methyl-5-ethyl-5-phenylbarbituric acid; 1-Methyl-5-phenyl-5-ethylbarbituric acid; 1-Methylphenobarbital; 5-Ethyl-1-methyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione; 5-Ethyl-1-methyl-5-phenylbarbituric acid; 5-Ethyl-5-phenyl-N-methyl-bartituric acid; 5-Ethyl-N-methyl-5-phenylbarbituric acid; 5-Phenyl-5-ethyl-3-methylbarbituric acid; 5-ethyl-1-methyl-5-phenyl-1,3-diazinane-2,4,6-trione; 5-ethyl-1-methyl-5-phenylpyrimidine-2,4,6(1H,3H,5H)-trione
|
||||
Drug Type |
Small molecular drug
|
||||
Indication | Anxiety disorder [ICD9: 300, 311; ICD10:F32, F40-F42] | Approved | [550692] | ||
Therapeutic Class |
Hypnotics and Sedatives
|
||||
Company |
Ovation Pharmaceuticals
|
||||
Structure |
Download2D MOL |
||||
Formula |
C13H14N2O3
|
||||
Canonical SMILES |
CCC1(C(=O)NC(=O)N(C1=O)C)C2=CC=CC=C2
|
||||
InChI |
1S/C13H14N2O3/c1-3-13(9-7-5-4-6-8-9)10(16)14-12(18)15(2)11(13)17/h4-8H,3H2,1-2H3,(H,14,16,18)
|
||||
InChIKey |
ALARQZQTBTVLJV-UHFFFAOYSA-N
|
||||
CAS Number |
CAS 115-38-8
|
||||
PubChem Compound ID | |||||
PubChem Substance ID |
10031, 5093039, 7847765, 7979946, 8147151, 8155794, 10504537, 14749710, 29215275, 29215276, 29226981, 46505197, 47833442, 48416217, 49874379, 56459436, 57324893, 76802480, 81093033, 87691917, 88488011, 92714690, 103224015, 104317381, 106801875, 117837484, 125823035, 127422109, 128099894, 134337969, 134974876, 137101290, 137240130, 144205153, 160964190, 164761780, 169763687, 177513116, 179226247, 181851673, 184548424, 226421831, 250086055, 252452819
|
||||
ChEBI ID |
ChEBI:6758
|
||||
SuperDrug ATC ID |
N03AA01
|
||||
SuperDrug CAS ID |
cas=000115388
|
||||
Target and Pathway | |||||
Target(s) | Gamma-aminobutyric acid receptor subunit alpha-1 | Target Info | Antagonist | [536555], [537688] | |
References | |||||
Ref 536555 | DrugBank: a knowledgebase for drugs, drug actions and drug targets. Nucleic Acids Res. 2008 Jan;36(Database issue):D901-6. Epub 2007 Nov 29. | ||||
Ref 537688 | Effect of barbiturates on polyphosphoinositide biosynthesis and protein kinase C activity in synaptosomes. Neuropharmacology. 1989 Dec;28(12):1317-23. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.