Drug General Information |
Drug ID |
D09TVP
|
Former ID |
DNC002588
|
Drug Name |
Cacodylate Ion
|
Drug Type |
Small molecular drug
|
Indication |
Discovery agent
|
Investigative |
[1]
|
Structure |
|
Download
2D MOL
3D MOL
|
Formula |
C2H7AsO2
|
Canonical SMILES |
C[As](=O)(C)O
|
InChI |
1S/C2H7AsO2/c1-3(2,4)5/h1-2H3,(H,4,5)
|
InChIKey |
OGGXGZAMXPVRFZ-UHFFFAOYSA-N
|
PubChem Compound ID |
|
PubChem Substance ID |
9516, 405276, 550112, 583643, 585540, 609263, 820929, 820955, 825024, 825305, 825315, 825331, 826127, 828436, 830633, 830847, 830886, 831497, 833146, 854580, 855157, 3152853, 5070549, 6436179, 8018167, 8022881, 8023029, 8027709, 8027881, 8028368, 8150092, 8151668, 10317216, 10317237, 10534914, 11335883, 11361122, 11364913, 11367475, 11370037, 11374068, 11378207, 11404479, 11405987, 11447883, 11447931, 11449379, 11462094, 11484895, 11488986
|
Target and Pathway |
Target(s) |
Thyroid hormone receptor beta-1 |
Target Info |
Inhibitor |
[1]
|
UDP-3-O-[3-hydroxymyristoyl] n-acetylglucosamine deacetylase |
Target Info |
Inhibitor |
[1]
|
Nitric-oxide synthase, endothelial |
Target Info |
Inhibitor |
[1]
|
Aspartate-semialdehydedehydrogenase |
Target Info |
Inhibitor |
[1]
|
Thioredoxin |
Target Info |
Inhibitor |
[1]
|
Calmodulin |
Target Info |
Inhibitor |
[1]
|
BioCyc Pathway
|
Citrulline-nitric oxide cycle
|
KEGG Pathway
|
Neuroactive ligand-receptor interaction
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Thyroid hormone signaling pathwaypae00540:Lipopolysaccharide biosynthesis
|
Metabolic pathwayshsa00330:Arginine and proline metabolism
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Metabolic pathways
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Calcium signaling pathway
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cGMP-PKG signaling pathway
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HIF-1 signaling pathway
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Sphingolipid signaling pathway
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PI3K-Akt signaling pathway
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VEGF signaling pathway
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Platelet activation
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Estrogen signaling pathway
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Oxytocin signaling pathwayhsa04014:Ras signaling pathway
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Rap1 signaling pathway
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cAMP signaling pathway
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Phosphatidylinositol signaling system
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Oocyte meiosis
|
Adrenergic signaling in cardiomyocytes
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Vascular smooth muscle contraction
|
Circadian entrainment
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Long-term potentiation
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Neurotrophin signaling pathway
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Dopaminergic synapse
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Olfactory transduction
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Phototransduction
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Inflammatory mediator regulation of TRP channels
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Insulin signaling pathway
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GnRH signaling pathway
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Melanogenesis
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Oxytocin signaling pathway
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Glucagon signaling pathway
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Salivary secretion
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Gastric acid secretion
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Alzheimer's disease
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Amphetamine addiction
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Alcoholism
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Pertussis
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Tuberculosis
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Glioma
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NetPath Pathway
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Wnt Signaling PathwayNetPath_14:IL2 Signaling Pathway
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RANKL Signaling PathwayNetPath_21:RANKL Signaling Pathway
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TSH Signaling Pathway
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PANTHER Pathway
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Angiogenesis
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Endothelin signaling pathway
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Interleukin signaling pathway
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PI3 kinase pathway
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VEGF signaling pathwayP00030:Hypoxia response via HIF activation
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Oxidative stress responseP06959:CCKR signaling map ST
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Pathway Interaction Database
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RXR and RAR heterodimerization with other nuclear receptorer_nongenomic_pathway:Plasma membrane estrogen receptor signaling
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Validated transcriptional targets of AP1 family members Fra1 and Fra2
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Angiopoietin receptor Tie2-mediated signaling
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Thromboxane A2 receptor signaling
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SHP2 signaling
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VEGFR1 specific signals
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Signaling events mediated by VEGFR1 and VEGFR2
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PAR1-mediated thrombin signaling eventsp38_mkk3_6pathway:p38 MAPK signaling pathway
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Signaling events mediated by PTP1B
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TNF receptor signaling pathwaybcr_5pathway:BCR signaling pathway
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p38 MAPK signaling pathway
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Calcineurin-regulated NFAT-dependent transcription in lymphocytes
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Role of Calcineurin-dependent NFAT signaling in lymphocytes
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IL2 signaling events mediated by PI3K
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IFN-gamma pathway
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Lissencephaly gene (LIS1) in neuronal migration and development
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ErbB1 downstream signaling
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Regulation of cytoplasmic and nuclear SMAD2/3 signaling
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Calcium signaling in the CD4+ TCR pathway
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Insulin-mediated glucose transport
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N-cadherin signaling events
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Cellular roles of Anthrax toxin
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Regulation of Ras family activation
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Downstream signaling in naï
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PathWhiz Pathway
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Purine MetabolismPW000564:Muscle/Heart Contraction
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Reactome
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Nuclear Receptor transcription pathwayR-HSA-1222556:ROS production in response to bacteria
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Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
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eNOS activation
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Nitric oxide stimulates guanylate cyclase
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VEGFR2 mediated vascular permeabilityR-HSA-2559580:Oxidative Stress Induced Senescence
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Detoxification of Reactive Oxygen Species
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TP53 Regulates Metabolic Genes
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The NLRP3 inflammasomeR-HSA-111933:Calmodulin induced events
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Platelet degranulation
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Translocation of GLUT4 to the plasma membrane
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DARPP-32 events
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Inactivation, recovery and regulation of the phototransduction cascade
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FCERI mediated Ca+2 mobilization
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Ca2+ pathway
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CREB phosphorylation through the activation of CaMKII
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Ras activation uopn Ca2+ infux through NMDA receptor
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Smooth Muscle Contraction
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VEGFR2 mediated vascular permeability
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VEGFR2 mediated cell proliferation
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RHO GTPases activate IQGAPs
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RAF/MAP kinase cascade
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Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
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WikiPathways
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SIDS Susceptibility Pathways
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Hematopoietic Stem Cell Differentiation
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Nuclear ReceptorsWP554:ACE Inhibitor Pathway
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EGF/EGFR Signaling Pathway
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Myometrial Relaxation and Contraction Pathways
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JAK/STAT
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Corticotropin-releasing hormone
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AGE/RAGE pathway
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Endothelin Pathways
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Leptin signaling pathway
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Effects of Nitric Oxide
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Metabolism of nitric oxide
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AngiogenesisWP2884:NRF2 pathway
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Nuclear Receptors Meta-Pathway
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Detoxification of Reactive Oxygen Species
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Human Complement System
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Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
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TNF alpha Signaling Pathway
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Metabolism of nucleotides
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Selenium Micronutrient NetworkWP2777:Translocation of GLUT4 to the Plasma Membrane
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Visual phototransduction
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Fc epsilon receptor (FCERI) signaling
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Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
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Signaling by the B Cell Receptor (BCR)
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Inositol phosphate metabolism
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DAG and IP3 signaling
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Opioid Signalling
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Muscle contraction
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Metabolism of carbohydrates
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References |
REF 1 | How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. |