| Drug General Information |
| Drug ID |
D0A8JP
|
| Former ID |
DNC008509
|
| Drug Name |
PARABEN
|
| Indication |
Discovery agent
|
Phase 3 |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Target and Pathway |
| Target(s) |
Carbonic anhydrase XIV |
Target Info |
Inhibitor |
[2]
|
|---|
| Carbonic anhydrase VI |
Target Info |
Inhibitor |
[2]
|
| Carbonic anhydrase IX |
Target Info |
Inhibitor |
[2]
|
| Carbonic anhydrase XII |
Target Info |
Inhibitor |
[2]
|
| Carbonic anhydrase II |
Target Info |
Inhibitor |
[2]
|
| Carbonic anhydrase |
Target Info |
Inhibitor |
[2]
|
| Carbonic anhydrase IV |
Target Info |
Inhibitor |
[2]
|
| Carbonic anhydrase I |
Target Info |
Inhibitor |
[2]
|
|
KEGG Pathway
|
Nitrogen metabolismhsa00910:Nitrogen metabolismhsa00910:Nitrogen metabolismhsa00910:Nitrogen metabolismhsa00910:Nitrogen metabolism
|
|
Proximal tubule bicarbonate reclamation
|
|
Collecting duct acid secretion
|
|
Gastric acid secretion
|
|
Pancreatic secretion
|
|
Bile secretionhsa00910:Nitrogen metabolism
|
|
Proximal tubule bicarbonate reclamationhsa00910:Nitrogen metabolism
|
|
NetPath Pathway
|
TGF_beta_Receptor Signaling PathwayNetPath_16:IL4 Signaling Pathway
|
|
EGFR1 Signaling Pathway
|
|
Pathway Interaction Database
|
HIF-1-alpha transcription factor networkcmyb_pathway:C-MYB transcription factor network
|
|
PathWhiz Pathway
|
Gastric Acid Production
|
|
Reactome
|
Reversible hydration of carbon dioxideR-HSA-1475029:Reversible hydration of carbon dioxideR-HSA-1234158:Regulation of gene expression by Hypoxia-inducible Factor
|
|
Reversible hydration of carbon dioxideR-HSA-1475029:Reversible hydration of carbon dioxideR-HSA-1237044:Erythrocytes take up carbon dioxide and release oxygen
|
|
Erythrocytes take up oxygen and release carbon dioxide
|
|
Reversible hydration of carbon dioxideR-HSA-1237044:Erythrocytes take up carbon dioxide and release oxygen
|
|
Reversible hydration of carbon dioxide
|
|
WikiPathways
|
Reversible Hydration of Carbon DioxideWP2770:Reversible Hydration of Carbon DioxideWP2877:Vitamin D Receptor Pathway
|
|
Reversible Hydration of Carbon Dioxide
|
|
Regulation of Hypoxia-inducible Factor (HIF) by OxygenWP2770:Reversible Hydration of Carbon Dioxide
|
|
miR-targeted genes in muscle cell - TarBase
|
|
miR-targeted genes in leukocytes - TarBase
|
|
miR-targeted genes in epithelium - TarBaseWP2770:Reversible Hydration of Carbon Dioxide
|
|
Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes
|
|
Uptake of Oxygen and Release of Carbon Dioxide by ErythrocytesWP2770:Reversible Hydration of Carbon Dioxide
|
|
Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes
|
| References |
| REF 1 | ClinicalTrials.gov (NCT01688479) Trial Comparing Calendula Officinalis With Aqueous Cream "Essex" to Treat Skin Reactions From Radiotherapy of Breast Cancer. U.S. National Institutes of Health. |
|---|
| REF 2 | Bioorg Med Chem. 2010 Mar 15;18(6):2159-64. Epub 2010 Feb 6.Carbonic anhydrase inhibitors. Inhibition of mammalian isoforms I-XIV with a series of natural product polyphenols and phenolic acids. |
|---|
