Drug Information
Drug General Information | |||||
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Drug ID |
D0E0WQ
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Former ID |
DAP001350
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Drug Name |
Barbital
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Synonyms |
Barbitale; Barbitalum; Barbitone; Barbitonum; DEBA; Diemal; Diemalum; Diethylbarbitone; Diethylmalonylurea; Dormileno; Dormonal; Ethylbarbital; Hypnogene; Malonal; Medinal; Sedeval; Uronal; Veroletten; Verolettin; Veronal; Vesperal; Barbital Faes Brand; Barbitale [DCIT]; Diethylbarbituric acid; Faes Brand of Barbital; Barbital (TN); Barbital (VAN); Barbital [INN:JAN]; Barbitalum [INN-Latin]; Veronal (TN); Barbital (JP15/INN); Kyselina 5,5-diethylbarbiturova; Kyselina 5,5-diethylbarbiturova [Czech]; 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5,5-diethyl-(9CI); 5,5-Diethyl-2,4,6(1H,3H,5H)-pyrimidinetrione; 5,5-Diethylbarbituric acid; 5,5-diethyl-1,3-diazinane-2,4,6-trione; 5,5-diethylpyrimidine-2,4,6(1H,3H,5H)-trione; 7979P
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Drug Type |
Small molecular drug
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Indication | Insomnia [ICD9: 307.41, 307.42, 327.0, 780.51, 780.52; ICD10:F51.0, G47.0] | Approved | [536555] | ||
Therapeutic Class |
Hypnotics and Sedatives
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Company |
Schering-Plough
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Structure |
Download2D MOL |
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Formula |
C8H12N2O3
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Canonical SMILES |
CCC1(C(=O)NC(=O)NC1=O)CC
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InChI |
1S/C8H12N2O3/c1-3-8(4-2)5(11)9-7(13)10-6(8)12/h3-4H2,1-2H3,(H2,9,10,11,12,13)
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InChIKey |
FTOAOBMCPZCFFF-UHFFFAOYSA-N
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CAS Number |
CAS 57-44-3
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PubChem Compound ID | |||||
PubChem Substance ID |
90340, 589068, 841531, 5611996, 5972305, 7848803, 8151540, 10527896, 11533956, 15219736, 24859202, 24891513, 29215357, 29215358, 29221466, 46508979, 47365376, 48334676, 48415603, 49874104, 50176612, 56459416, 57321239, 57648640, 58694180, 103165760, 104300174, 118189912, 124892181, 125332012, 125736552, 126677738, 127897641, 134338564, 134970868, 137003152, 137204186, 139051997, 144076045, 144205203, 152042447, 160964740, 163120017, 164836116, 164836117, 165319864, 170465829, 175265443, 175442207, 175611463
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ChEBI ID |
ChEBI:31252
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SuperDrug ATC ID |
N05CA04
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SuperDrug CAS ID |
cas=000057443
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Target and Pathway | |||||
Target(s) | Gamma-aminobutyric acid receptor subunit alpha-1 | Target Info | Antagonist | [536555], [537688] | |
References | |||||
Ref 536555 | DrugBank: a knowledgebase for drugs, drug actions and drug targets. Nucleic Acids Res. 2008 Jan;36(Database issue):D901-6. Epub 2007 Nov 29. | ||||
Ref 537688 | Effect of barbiturates on polyphosphoinositide biosynthesis and protein kinase C activity in synaptosomes. Neuropharmacology. 1989 Dec;28(12):1317-23. |
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