Drug General Information
Drug ID	D0F6TM
Former ID	DNC012711
Drug Name	(6-Hydroxy-2-oxo-2H-quinolin-1-yl)-acetic acid
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[533420]
Structure		Download 2D MOL 3D MOL
Formula	C11H9NO4
Canonical SMILES	C1=CC2=C(C=CC(=O)N2CC(=O)O)C=C1O
InChI	1S/C11H9NO4/c13-8-2-3-9-7(5-8)1-4-10(14)12(9)6-11(15)16/h1-5,13H,6H2,(H,15,16)
InChIKey	VDYFIKQEBBKQES-UHFFFAOYSA-N
PubChem Compound ID	13683080
Target and Pathway
Target(s)	Aldose reductase	Target Info	Inhibitor	[533420]
BioCyc Pathway	Methylglyoxal degradation III
	Acetone degradation I (to methylglyoxal)
KEGG Pathway	Pentose and glucuronate interconversions
	Fructose and mannose metabolism
	Galactose metabolism
	Glycerolipid metabolism
	Metabolic pathways
NetPath Pathway	IL1 Signaling Pathway
	TGF_beta_Receptor Signaling Pathway
PathWhiz Pathway	Fructose and Mannose Degradation
	Pyruvate Metabolism
	Pterine Biosynthesis
	Glycerolipid Metabolism
	Galactose Metabolism
WikiPathways	Metapathway biotransformation
	Polyol Pathway
	Metabolism of steroid hormones and vitamin D
References
Ref 533420	J Med Chem. 1986 Oct;29(10):2024-8.Synthesis and aldose reductase inhibitory activity of substituted 2-oxoquinoline-1-acetic acid derivatives.
Ref 533420	J Med Chem. 1986 Oct;29(10):2024-8.Synthesis and aldose reductase inhibitory activity of substituted 2-oxoquinoline-1-acetic acid derivatives.

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