Drug General Information
Drug ID
D0F8RA
Former ID
DAP000002
Drug Name
Theophylline
Synonyms
Accurbron; Aerobin; Aerolate; Afonilm; Afonilum; Aminophylline; Aquaphyllin; Armophylline; Asmalix; Asmax; Austyn; Bilordyl; Bronchoparat; Bronchoretard; Bronkodyl; Bronkotabs; Cetraphylline; Chronophyllin; ConstantT; Diffumal; Dimethylxanthine; Doraphyllin; Duraphyl; Duraphyllin; Egifilin; Elixex; Elixicon; Elixomin; Elixophyllin; Elixophylline; Etheophyl; Euphylong; Hylate; LASMA; LaBID; Labophylline; Lanophyllin; Liquophylline; Maphylline; Medaphyllin; Mudrane; Nuelin; Optiphyllin; Parkophyllin; Physpan; Pseudotheophylline; Pulmidur; Quibron; Respbid; Respicur; Respid; SloPhyllin; Solosin; SomophyllinT; Sustaire; Synophylate; Talotren; Tefamin; Teofilina; Teofyllamin; Teolair; Teonova;Teosona; Tesona; Theacitin; Theobid; Theochron; Theocin; Theoclear; Theocontin; Theodel; Theodrip; Theodur; Theofol; Theograd; Theokin; Theolair; Theolix; Theolixir; Theonite; Theopek; Theophyl; Theophyline; Theophyllin; Theoplus; Theospan; Theostat; Theotard; Theovent; Unifyl; Unilong; Uniphyl; Uniphyllin; Uniphylline; Xanthium; Xantivent; Aerolate III; Aerolate SR; Afonilum Retard; Bronchodid Duracap; Bronkodyl SR; Choledyl SA; Constant T; Elixophyllin SR; Nuelin SA; Quibron T; Quibron T SR; Quibron TSR; Slo Phyllin; Somophyllin CRT; Somophyllin T; Spophyllin retard; THEOBID JR; Telbans DrySyrup; Teofilina [Polish]; Theal tablets; Theo Dur; Theo von ct; Theobid Duracap; Theoclear LA; Theodur Dry Syrup; Theodur G; Theona P; Uniphyllin continus; GS 2591A; Teocen 200; Theo 24; Theo24; Theoclear 80; Theostat 80; X 115; Acet-theocin; Constant-T; Ct, theo von; Elixophyllin (TN); Elixophyllin(e); Nuelin S.A; Pro-vent; Pulmo-Timelets; Quibron T-SR; Quibron T/SR; Quibron-T; Slo-bid; Slo-phyllin; Somophyllin-CRT; Somophyllin-DF; Somophyllin-t; T-Phyl; Telb-DS; Theo-11; Theo-24; Theo-DS; Theo-Nite; Theo-Organidin; Theo-Sav; Theo-dur; Theobid Jr.; Theoclair-SR; Theoclear-200; Theoclear-80;Theodur G (TN); Theolair (TN); Theolair-SR; Theophyl-225; Theophyl-SR; Theophylline (JP15); Theophylline-SR; Uni-Dur; Uniphyl (TN); Von ct, theo; Nuelin S.A.; Quibron-T/SR; Quibron-t (TN); Theo-24 (TN); Theo-Dur-Sprinkle; Theophylline-[8-3H; Theoclear L.A.-130; 1,3 Dimethylxanthine; 1,3-Dimethylxanthine; 1H-purine-2,6-dione
Drug Type
Small molecular drug
Indication Chronic obstructive pulmonary disease [ICD9: 490-492, 494-496; ICD10:J40-J44, J47] Approved [467474], [536481]
Therapeutic Class
Bronchodilator Agents
Company
Purdue Pharma
Structure
Download
2D MOL

3D MOL

Formula
C7H8N4O2
InChI
InChI=1S/C7H8N4O2/c1-10-5-4(8-3-9-5)6(12)11(2)7(10)13/h3H,1-2H3,(H,8,9)
InChIKey
ZFXYFBGIUFBOJW-UHFFFAOYSA-N
CAS Number
CAS 58-55-9
PubChem Compound ID
PubChem Substance ID
ChEBI ID
ChEBI:28177
SuperDrug ATC ID
R03DA04
SuperDrug CAS ID
cas=000058559
Target and Pathway
Target(s) Adenosine receptor Target Info Antagonist [536157], [536501]
References
Ref 467474(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 413).
Ref 536481Non-corticosteroid therapy for the long-term control of asthma. Expert Opin Pharmacother. 2007 Sep;8(13):2077-87.
Ref 536157Role of adenosine in airway inflammation in an allergic mouse model of asthma. Int Immunopharmacol. 2006 Jan;6(1):36-45. Epub 2005 Aug 1.
Ref 536501Emerging adenosine receptor agonists. Expert Opin Emerg Drugs. 2007 Sep;12(3):479-92.

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