Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0FF3D
|
||||
| Former ID |
DNC000929
|
||||
| Drug Name |
Metazamide
|
||||
| Drug Type |
Small molecular drug
|
||||
| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C11H12N2O2
|
||||
| Canonical SMILES |
CC1=CNC(=O)N1C2=CC=C(C=C2)OC
|
||||
| InChI |
1S/C11H12N2O2/c1-8-7-12-11(14)13(8)9-3-5-10(15-2)6-4-9/h3-7H,1-2H3,(H,12,14)
|
||||
| InChIKey |
NHUPEUMBGMETKD-UHFFFAOYSA-N
|
||||
| CAS Number |
CAS 347396-82-1
|
||||
| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Glucose-6-phosphate dehydrogenase | Target Info | Inhibitor | [1] | |
| BioCyc Pathway | Pentose phosphate pathway | ||||
| Pentose phosphate pathway (oxidative branch) | |||||
| KEGG Pathway | Pentose phosphate pathway | ||||
| Glutathione metabolism | |||||
| Metabolic pathways | |||||
| Biosynthesis of antibiotics | |||||
| Carbon metabolism | |||||
| Central carbon metabolism in cancer | |||||
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
| PathWhiz Pathway | Pentose Phosphate Pathway | ||||
| Warburg Effect | |||||
| Reactome | TP53 Regulates Metabolic Genes | ||||
| WikiPathways | Sulfation Biotransformation Reaction | ||||
| NRF2 pathway | |||||
| Nuclear Receptors Meta-Pathway | |||||
| Vitamin D Receptor Pathway | |||||
| miR-targeted genes in muscle cell - TarBase | |||||
| miR-targeted genes in lymphocytes - TarBase | |||||
| miR-targeted genes in leukocytes - TarBase | |||||
| miR-targeted genes in epithelium - TarBase | |||||
| Cori Cycle | |||||
| Metabolism of carbohydrates | |||||
| Pentose Phosphate Pathway | |||||
| Glutathione metabolism | |||||
| References | |||||
| REF 1 | Glucose utilization and activity of glucose-6-phosphate dehydrogenase, isocitrate dehydrogenase and malate dehydrogenase in rat erythrocytes after treatment with tuberculostatic agents. Vopr Med Khim. 1986 Sep-Oct;32(5):32-5. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.