Drug Information

Drug General Information
Drug ID
D0G6RT
Former ID
DNC002628
Drug Name
(R)-4-Amino-Isoxazolidin-3-One
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551393]
Structure
Download
2D MOL

3D MOL
Formula
C3H6N2O2
Canonical SMILES
C1C(C(=O)NO1)N
InChI
1S/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6)/t2-/m1/s1
InChIKey
DYDCUQKUCUHJBH-UWTATZPHSA-N
PubChem Compound ID
6234
PubChem Substance ID
10257, 602895, 829389, 841629, 3139717, 7847941, 7885338, 7979010, 8149277, 8153915, 11110913, 11110914, 11110915, 11112194, 11112195, 11335273, 11360512, 11363754, 11366316, 11368878, 11371441, 11374029, 11377040, 11461484, 11467117, 11468237, 11483744, 11486765, 11487900, 11490187, 11492120, 11494674, 12014545, 15170469, 17404815, 24277962, 24858076, 24892907, 24892979, 25622405, 26611680, 26679210, 26719637, 29214856, 29225230, 46386864, 46392863, 46506865, 46507135, 47216632
Target and Pathway
Target(s) Alanine racemase,biosynthetic Target Info Inhibitor [551393]
NMDA receptor subunit NR1 Target Info Inhibitor [551393]
KEGG Pathway Ras signaling pathway
Rap1 signaling pathway
Calcium signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Circadian entrainment
Long-term potentiation
Glutamatergic synapse
Alzheimer's disease
Amyotrophic lateral sclerosis (ALS)
Huntington's disease
Cocaine addiction
Amphetamine addiction
Nicotine addiction
Alcoholism
PANTHER Pathway Huntington disease
Ionotropic glutamate receptor pathway
Metabotropic glutamate receptor group III pathway
Metabotropic glutamate receptor group I pathway
Muscarinic acetylcholine receptor 1 and 3 signaling pathway
Reactome EPHB-mediated forward signaling
Unblocking of NMDA receptor, glutamate binding and activation
CREB phosphorylation through the activation of CaMKII
Ras activation uopn Ca2+ infux through NMDA receptor
RAF/MAP kinase cascade
WikiPathways SIDS Susceptibility Pathways
Hypothetical Network for Drug Addiction
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Spinal Cord Injury
BDNF signaling pathway
Alzheimers Disease
References
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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