Drug General Information
Drug ID	D0I0ML
Former ID	DNC007747
Drug Name	2-(2'-methyl-biphenyl-3-yl)-ethylamine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[528780]
Structure		Download 2D MOL 3D MOL
Formula	C15H17N
Canonical SMILES	CC1=CC=CC=C1C2=CC(=CC=C2)CCN
InChI	1S/C15H17N/c1-12-5-2-3-8-15(12)14-7-4-6-13(11-14)9-10-16/h2-8,11H,9-10,16H2,1H3
InChIKey	KQRAKUVQYREATE-UHFFFAOYSA-N
PubChem Compound ID	35985234
Target and Pathway
Target(s)	5-hydroxytryptamine 1A receptor	Target Info	Inhibitor	[528780]
	5-hydroxytryptamine 7 receptor	Target Info	Inhibitor	[528780]
KEGG Pathway	cAMP signaling pathway
	Neuroactive ligand-receptor interaction
	Serotonergic synapsehsa04014:Ras signaling pathway
	Calcium signaling pathway
	Serotonergic synapse
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
	5HT1 type receptor mediated signaling pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PathWhiz Pathway	Excitatory Neural Signalling Through 5-HTR 7 and Serotonin
Reactome	Serotonin receptors
	G alpha (i) signalling eventsR-HSA-390666:Serotonin receptors
	G alpha (s) signalling events
WikiPathways	Serotonin HTR1 Group and FOS Pathway
	SIDS Susceptibility Pathways
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signalingWP734:Serotonin Receptor 4/6/7 and NR3C Signaling
	GPCR downstream signaling
	GPCRs, Other
References
Ref 528780	Bioorg Med Chem Lett. 2007 Jun 1;17(11):3018-22. Epub 2007 Mar 23.Novel aminoethylbiphenyls as 5-HT7 receptor ligands.
Ref 528780	Bioorg Med Chem Lett. 2007 Jun 1;17(11):3018-22. Epub 2007 Mar 23.Novel aminoethylbiphenyls as 5-HT7 receptor ligands.

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