Drug Information

Drug General Information
Drug ID
D0I4ME
Former ID
DNC003311
Drug Name
MMDA
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551393]
Structure
Download
2D MOL

3D MOL
Formula
C11H15NO3
Canonical SMILES
CC(CC1=CC2=C(C(=C1)OC)OCO2)N
InChI
1S/C11H15NO3/c1-7(12)3-8-4-9(13-2)11-10(5-8)14-6-15-11/h4-5,7H,3,6,12H2,1-2H3
InChIKey
YQYUWUKDEVZFDB-UHFFFAOYSA-N
CAS Number
CAS 13674-05-0
PubChem Compound ID
26175
PubChem Substance ID
841184, 8168993, 11078692, 15291764, 29293041, 46506802, 50004586, 57310189, 80019684, 103357129, 104296574, 117603350, 124954060, 129835394, 134990556, 137005509, 160964709, 180370896, 227920482, 249912023
Target and Pathway
Target(s) Sodium-dependent noradrenaline transporter Target Info Modulator [551393]
Synaptic vesicle amine transporter Target Info Antagonist [551393]
Amine oxidase [flavin-containing] B Target Info Antagonist [551393]
Sodium-dependent dopamine transporter Target Info Modulator [551393]
Amine oxidase [flavin-containing] A Target Info Antagonist [551393]
Sodium-dependent serotonin transporter Target Info Modulator [551393]
5-hydroxytryptamine 2A receptor Target Info Agonist [551393]
BioCyc Pathway Superpathway of tryptophan utilization
Tryptophan degradation via tryptamine
Dopamine degradation
Putrescine degradation III
Noradrenaline and adrenaline degradationPWY66-401:Superpathway of tryptophan utilization
Noradrenaline and adrenaline degradation
Serotonin degradation
Superpathway of melatonin degradation
Melatonin degradation II
KEGG Pathway Synaptic vesicle cycle
Serotonergic synapse
Dopaminergic synapse
Parkinson's disease
Cocaine addiction
Amphetamine addiction
Alcoholismhsa00260:Glycine, serine and threonine metabolism
Arginine and proline metabolism
Histidine metabolism
Tyrosine metabolism
Phenylalanine metabolism
Tryptophan metabolism
Drug metabolism - cytochrome P450
Metabolic pathways
Alcoholismhsa04728:Dopaminergic synapse
Alcoholismhsa04726:Serotonergic synapsehsa04020:Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Inflammatory mediator regulation of TRP channels
NetPath Pathway IL4 Signaling PathwayNetPath_11:TCR Signaling Pathway
PANTHER Pathway Adrenaline and noradrenaline biosynthesisP00001:Adrenaline and noradrenaline biosynthesis
5HT1 type receptor mediated signaling pathway
5HT2 type receptor mediated signaling pathway
5HT3 type receptor mediated signaling pathway
5HT4 type receptor mediated signaling pathway
Dopamine receptor mediated signaling pathway
Nicotine pharmacodynamics pathway
CCKR signaling map STP00001:Adrenaline and noradrenaline biosynthesis
5-Hydroxytryptamine degredation
Dopamine receptor mediated signaling pathwayP00001:Adrenaline and noradrenaline biosynthesis
Parkinson disease
Dopamine receptor mediated signaling pathwayP04373:5HT1 type receptor mediated signaling pathway
5HT4 type receptor mediated signaling pathwayP04374:5HT2 type receptor mediated signaling pathway
Pathway Interaction Database Alpha-synuclein signalingalphasynuclein_pathway:Alpha-synuclein signaling
PathWhiz Pathway Histidine Metabolism
Tyrosine Metabolism
Glycine and Serine Metabolism
Reactome Na+/Cl- dependent neurotransmitter transportersR-HSA-181430:Norepinephrine Neurotransmitter Release Cycle
Na+/Cl- dependent neurotransmitter transportersR-HSA-442660:Na+/Cl- dependent neurotransmitter transportersR-HSA-181430:Norepinephrine Neurotransmitter Release CycleR-HSA-390666:Serotonin receptors
G alpha (q) signalling events
WikiPathways Monoamine Transport
NRF2 pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsWP2855:Dopaminergic Neurogenesis
Synaptic Vesicle Pathway
Neurotransmitter Release Cycle
Nicotine Activity on Dopaminergic NeuronsWP465:Tryptophan metabolism
Dopamine metabolism
Phase 1 - Functionalization of compoundsWP727:Monoamine Transport
Dopaminergic Neurogenesis
Parkinsons Disease Pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
Neurotransmitter Clearance In The Synaptic CleftWP706:SIDS Susceptibility Pathways
Biogenic Amine Synthesis
Oxidative Stress
Phase 1 - Functionalization of compounds
Neurotransmitter Clearance In The Synaptic Cleft
Serotonin Transporter ActivityWP727:Monoamine Transport
SIDS Susceptibility Pathways
Serotonin Transporter ActivityWP733:Serotonin Receptor 2 and STAT3 Signaling
Serotonin Receptor 2 and ELK-SRF/GATA4 signaling
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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