Drug Information
Drug General Information | |||||
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Drug ID |
D0I6XA
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Former ID |
DNC004384
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Drug Name |
(2R,3S)-3-(6-Amino-purin-9-yl)-nonan-2-ol
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Synonyms |
3-(6-Amino-purin-9-yl)-nonan-2-ol
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Indication | Discovery agent | Investigative | [527549] | ||
Structure |
Download2D MOL |
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Canonical SMILES |
CCCCCCC(C(C)O)N1C=NC2=C1N=CN=C2N
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InChI |
1S/C14H23N5O/c1-3-4-5-6-7-11(10(2)20)19-9-18-12-13(15)16-8-17-14(12)19/h8-11,20H,3-7H2,1-2H3,(H2,15,16,17)/t10-,11+/m1/s1
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InChIKey |
IOSAAWHGJUZBOG-MNOVXSKESA-N
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Target and Pathway | |||||
Target(s) | Adenosine A3 receptor | Target Info | Inhibitor | [533722] | |
CGMP-dependent3',5'-cyclic phosphodiesterase | Target Info | Inhibitor | [527549] | ||
Adenosine A2a receptor | Target Info | Inhibitor | [533722] | ||
NetPath Pathway | TSH Signaling Pathway | ||||
Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
References | |||||
Ref 527549 | J Med Chem. 2005 May 19;48(10):3449-62.The next generation of phosphodiesterase inhibitors: structural clues to ligand and substrate selectivity of phosphodiesterases. | ||||
Ref 533722 | J Med Chem. 1995 May 12;38(10):1720-35.Structure-activity relationships of 9-alkyladenine and ribose-modified adenosine derivatives at rat A3 adenosine receptors. |
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