Drug General Information
Drug ID
D0IF8Z
Former ID
DNC012705
Drug Name
(4-Methyl-2-oxo-2H-quinolin-1-yl)-acetic acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [533420]
Structure
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2D MOL

3D MOL

Formula
C12H11NO3
Canonical SMILES
CC1=CC(=O)N(C2=CC=CC=C12)CC(=O)O
InChI
1S/C12H11NO3/c1-8-6-11(14)13(7-12(15)16)10-5-3-2-4-9(8)10/h2-6H,7H2,1H3,(H,15,16)
InChIKey
VKKWCKNFSMMXJZ-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) Aldose reductase Target Info Inhibitor [533420]
BioCyc Pathway Methylglyoxal degradation III
Acetone degradation I (to methylglyoxal)
KEGG Pathway Pentose and glucuronate interconversions
Fructose and mannose metabolism
Galactose metabolism
Glycerolipid metabolism
Metabolic pathways
NetPath Pathway IL1 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
PathWhiz Pathway Fructose and Mannose Degradation
Pyruvate Metabolism
Pterine Biosynthesis
Glycerolipid Metabolism
Galactose Metabolism
WikiPathways Metapathway biotransformation
Polyol Pathway
Metabolism of steroid hormones and vitamin D
References
Ref 533420J Med Chem. 1986 Oct;29(10):2024-8.Synthesis and aldose reductase inhibitory activity of substituted 2-oxoquinoline-1-acetic acid derivatives.
Ref 533420J Med Chem. 1986 Oct;29(10):2024-8.Synthesis and aldose reductase inhibitory activity of substituted 2-oxoquinoline-1-acetic acid derivatives.

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