Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0J2NS
|
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| Former ID |
DNC000223
|
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| Drug Name |
Anti-D
|
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| Drug Type |
Small molecular drug
|
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| Indication | Idiopathic thrombocytopenic purpura [ICD9: 287.31; ICD10:D69.3] | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C6H14ClNO5
|
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| Canonical SMILES |
C(C1C(C(C(C(O1)O)N)O)O)O.Cl
|
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| InChI |
1S/C6H13NO5.ClH/c7-3-5(10)4(9)2(1-8)12-6(3)11;/h2-6,8-11H,1,7H2;1H/t2-,3-,4-,5-,6-;/m1./s1
|
||||
| InChIKey |
QKPLRMLTKYXDST-OCOFDJSDSA-N
|
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| CAS Number |
CAS 66-84-2
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| SuperDrug ATC ID |
M01AX05
|
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| SuperDrug CAS ID |
cas=003416248
|
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| Target and Pathway | |||||
| Target(s) | D(2) dopamine receptor | Target Info | Antagonist | [1] | |
| KEGG Pathway | Rap1 signaling pathway | ||||
| cAMP signaling pathway | |||||
| Neuroactive ligand-receptor interaction | |||||
| Gap junction | |||||
| Dopaminergic synapse | |||||
| Parkinson's disease | |||||
| Cocaine addiction | |||||
| Alcoholism | |||||
| PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | |||||
| Dopamine receptor mediated signaling pathway | |||||
| Nicotine pharmacodynamics pathway | |||||
| Reactome | Dopamine receptors | ||||
| G alpha (i) signalling events | |||||
| WikiPathways | Hypothetical Network for Drug Addiction | ||||
| Monoamine GPCRs | |||||
| GPCRs, Class A Rhodopsin-like | |||||
| Genes and (Common) Pathways Underlying Drug Addiction | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| Nicotine Activity on Dopaminergic Neurons | |||||
| References | |||||
| REF 1 | Emerging drugs for idiopathic thrombocytopenic purpura in adults. Expert Opin Emerg Drugs. 2008 Jun;13(2):237-54. | ||||
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