Drug Information
Drug General Information | |||||
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Drug ID |
D0J2NS
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Former ID |
DNC000223
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Drug Name |
Anti-D
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Drug Type |
Small molecular drug
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Indication | Idiopathic thrombocytopenic purpura [ICD9: 287.31; ICD10:D69.3] | Investigative | [1] | ||
Structure |
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Download2D MOL |
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Formula |
C6H14ClNO5
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Canonical SMILES |
C(C1C(C(C(C(O1)O)N)O)O)O.Cl
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InChI |
1S/C6H13NO5.ClH/c7-3-5(10)4(9)2(1-8)12-6(3)11;/h2-6,8-11H,1,7H2;1H/t2-,3-,4-,5-,6-;/m1./s1
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InChIKey |
QKPLRMLTKYXDST-OCOFDJSDSA-N
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CAS Number |
CAS 66-84-2
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
SuperDrug ATC ID |
M01AX05
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SuperDrug CAS ID |
cas=003416248
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Target and Pathway | |||||
Target(s) | D(2) dopamine receptor | Target Info | Antagonist | [1] | |
KEGG Pathway | Rap1 signaling pathway | ||||
cAMP signaling pathway | |||||
Neuroactive ligand-receptor interaction | |||||
Gap junction | |||||
Dopaminergic synapse | |||||
Parkinson's disease | |||||
Cocaine addiction | |||||
Alcoholism | |||||
PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | |||||
Dopamine receptor mediated signaling pathway | |||||
Nicotine pharmacodynamics pathway | |||||
Reactome | Dopamine receptors | ||||
G alpha (i) signalling events | |||||
WikiPathways | Hypothetical Network for Drug Addiction | ||||
Monoamine GPCRs | |||||
GPCRs, Class A Rhodopsin-like | |||||
Genes and (Common) Pathways Underlying Drug Addiction | |||||
GPCR ligand binding | |||||
GPCR downstream signaling | |||||
Nicotine Activity on Dopaminergic Neurons | |||||
References | |||||
REF 1 | Emerging drugs for idiopathic thrombocytopenic purpura in adults. Expert Opin Emerg Drugs. 2008 Jun;13(2):237-54. | ||||
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