Drug General Information
Drug ID	D0J7MD
Former ID	DNC012707
Drug Name	(6-Methoxy-2-oxo-2H-quinolin-1-yl)-acetic acid
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[533420]
Structure		Download 2D MOL 3D MOL
Formula	C12H11NO4
Canonical SMILES	COC1=CC2=C(C=C1)N(C(=O)C=C2)CC(=O)O
InChI	1S/C12H11NO4/c1-17-9-3-4-10-8(6-9)2-5-11(14)13(10)7-12(15)16/h2-6H,7H2,1H3,(H,15,16)
InChIKey	CHNXZDVEGNIZLG-UHFFFAOYSA-N
PubChem Compound ID	13683078
Target and Pathway
Target(s)	Aldose reductase	Target Info	Inhibitor	[533420]
BioCyc Pathway	Methylglyoxal degradation III
	Acetone degradation I (to methylglyoxal)
KEGG Pathway	Pentose and glucuronate interconversions
	Fructose and mannose metabolism
	Galactose metabolism
	Glycerolipid metabolism
	Metabolic pathways
NetPath Pathway	IL1 Signaling Pathway
	TGF_beta_Receptor Signaling Pathway
PathWhiz Pathway	Fructose and Mannose Degradation
	Pyruvate Metabolism
	Pterine Biosynthesis
	Glycerolipid Metabolism
	Galactose Metabolism
WikiPathways	Metapathway biotransformation
	Polyol Pathway
	Metabolism of steroid hormones and vitamin D
References
Ref 533420	J Med Chem. 1986 Oct;29(10):2024-8.Synthesis and aldose reductase inhibitory activity of substituted 2-oxoquinoline-1-acetic acid derivatives.
Ref 533420	J Med Chem. 1986 Oct;29(10):2024-8.Synthesis and aldose reductase inhibitory activity of substituted 2-oxoquinoline-1-acetic acid derivatives.

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