Drug General Information
Drug ID	D0L7MI
Former ID	DNC011408
Drug Name	7-Hydroxy-6-nitro-2-phenyl-chromen-4-one
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[525506]
Structure		Download 2D MOL 3D MOL
Formula	C15H9NO5
Canonical SMILES	C1=CC=C(C=C1)C2=CC(=O)C3=CC(=C(C=C3O2)O)[N+](=O)[O-]
InChI	1S/C15H9NO5/c17-12-7-14(9-4-2-1-3-5-9)21-15-8-13(18)11(16(19)20)6-10(12)15/h1-8,18H
InChIKey	KJSLXXZBGFZOAH-UHFFFAOYSA-N
PubChem Compound ID	10755384
Target and Pathway
Target(s)	Aldose reductase	Target Info	Inhibitor	[525506]
BioCyc Pathway	Methylglyoxal degradation III
	Acetone degradation I (to methylglyoxal)
KEGG Pathway	Pentose and glucuronate interconversions
	Fructose and mannose metabolism
	Galactose metabolism
	Glycerolipid metabolism
	Metabolic pathways
NetPath Pathway	IL1 Signaling Pathway
	TGF_beta_Receptor Signaling Pathway
PathWhiz Pathway	Fructose and Mannose Degradation
	Pyruvate Metabolism
	Pterine Biosynthesis
	Glycerolipid Metabolism
	Galactose Metabolism
WikiPathways	Metapathway biotransformation
	Polyol Pathway
	Metabolism of steroid hormones and vitamin D
References
Ref 525506	J Med Chem. 1999 Jun 3;42(11):1881-93.1-Benzopyran-4-one antioxidants as aldose reductase inhibitors.
Ref 525506	J Med Chem. 1999 Jun 3;42(11):1881-93.1-Benzopyran-4-one antioxidants as aldose reductase inhibitors.

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