Drug Information
Drug General Information | |||||
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Drug ID |
D0LS4U
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Former ID |
DIB007775
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Drug Name |
Etrabamine
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Synonyms |
14839-JL
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Drug Type |
Small molecular drug
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Indication | Parkinson's disease [ICD9: 332; ICD10:G20] | Terminated | [1] | ||
Company |
Chiesi SA
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Structure |
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Download2D MOL |
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Formula |
C8H12N2S
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Canonical SMILES |
c12c(ncs1)CCC(C2)NC
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CAS Number |
CAS 70590-58-8
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | D(2) dopamine receptor | Target Info | Modulator | [2] | |
KEGG Pathway | Rap1 signaling pathway | ||||
cAMP signaling pathway | |||||
Neuroactive ligand-receptor interaction | |||||
Gap junction | |||||
Dopaminergic synapse | |||||
Parkinson's disease | |||||
Cocaine addiction | |||||
Alcoholism | |||||
PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | |||||
Dopamine receptor mediated signaling pathway | |||||
Nicotine pharmacodynamics pathway | |||||
Reactome | Dopamine receptors | ||||
G alpha (i) signalling events | |||||
WikiPathways | Hypothetical Network for Drug Addiction | ||||
Monoamine GPCRs | |||||
GPCRs, Class A Rhodopsin-like | |||||
Genes and (Common) Pathways Underlying Drug Addiction | |||||
GPCR ligand binding | |||||
GPCR downstream signaling | |||||
Nicotine Activity on Dopaminergic Neurons | |||||
References | |||||
REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003368) | ||||
REF 2 | WO patent application no. 2009,0568,11, Medicaments. | ||||
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