Drug Information
Drug General Information | |||||
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Drug ID |
D0N6FZ
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Former ID |
DIB015711
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Drug Name |
WS-50030
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Synonyms |
WS-50030; Dual dopamine D2 partial agonist/serotonin reuptake inhibitor (schizophrenia); Dual dopamine D2 partial agonist/serotonin reuptake inhibitor (schizophrenia), Pfizer/Solvay
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Drug Type |
Small molecular drug
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Indication | Schizophrenia [ICD9: 295; ICD10:F20] | Investigative | [1] | ||
Company |
Wyeth
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Structure |
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Download2D MOL |
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Formula |
C23H25N3O2
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Canonical SMILES |
C1=C(CCCN2CCN(c3cccc4c3oc(=O)[nH]4)CC2)c2c(C1)cccc2
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | D(2) dopamine receptor | Target Info | Agonist | [1] | |
KEGG Pathway | Rap1 signaling pathway | ||||
cAMP signaling pathway | |||||
Neuroactive ligand-receptor interaction | |||||
Gap junction | |||||
Dopaminergic synapse | |||||
Parkinson's disease | |||||
Cocaine addiction | |||||
Alcoholism | |||||
PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | |||||
Dopamine receptor mediated signaling pathway | |||||
Nicotine pharmacodynamics pathway | |||||
Reactome | Dopamine receptors | ||||
G alpha (i) signalling events | |||||
WikiPathways | Hypothetical Network for Drug Addiction | ||||
Monoamine GPCRs | |||||
GPCRs, Class A Rhodopsin-like | |||||
Genes and (Common) Pathways Underlying Drug Addiction | |||||
GPCR ligand binding | |||||
GPCR downstream signaling | |||||
Nicotine Activity on Dopaminergic Neurons | |||||
References | |||||
REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 215). | ||||
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