Drug General Information
Drug ID	D0OC4B
Former ID	DNC011220
Drug Name	7-Hydroxy-4-phenylcoumarin
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[531138]
Structure		Download 2D MOL 3D MOL
Formula	C15H10O3
Canonical SMILES	C1=CC=C(C=C1)C2=CC(=O)OC3=C2C=CC(=C3)O
InChI	1S/C15H10O3/c16-11-6-7-12-13(10-4-2-1-3-5-10)9-15(17)18-14(12)8-11/h1-9,16H
InChIKey	IVJMJRRORVMRJJ-UHFFFAOYSA-N
PubChem Compound ID	5357479
Target and Pathway
Target(s)	Aldose reductase	Target Info	Inhibitor	[531138]
BioCyc Pathway	Methylglyoxal degradation III
	Acetone degradation I (to methylglyoxal)
KEGG Pathway	Pentose and glucuronate interconversions
	Fructose and mannose metabolism
	Galactose metabolism
	Glycerolipid metabolism
	Metabolic pathways
NetPath Pathway	IL1 Signaling Pathway
	TGF_beta_Receptor Signaling Pathway
PathWhiz Pathway	Fructose and Mannose Degradation
	Pyruvate Metabolism
	Pterine Biosynthesis
	Glycerolipid Metabolism
	Galactose Metabolism
WikiPathways	Metapathway biotransformation
	Polyol Pathway
	Metabolism of steroid hormones and vitamin D
References
Ref 531138	Bioorg Med Chem Lett. 2010 Oct 1;20(19):5630-3. Epub 2010 Aug 12.6,7-Dihydroxy-4-phenylcoumarin as inhibitor of aldose reductase 2.
Ref 531138	Bioorg Med Chem Lett. 2010 Oct 1;20(19):5630-3. Epub 2010 Aug 12.6,7-Dihydroxy-4-phenylcoumarin as inhibitor of aldose reductase 2.

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