Drug General Information
Drug ID
D0P0KF
Former ID
DAP000672
Drug Name
Clobazam
Synonyms
Caastilium; Chlorepin; Clobazamum; Clorepin; Frisium; Mystan; Noiafren; Odipam; Urbadan; Urbanil; Urbanyl; H 4723; HR 376; LM 2717; Clobazamum [INN-Latin]; Frisium (TN); H-4723; LM-2717; Mystan (TN); RU-4723; Urbanol (TN); Clobazam [USAN:BAN:INN]; Clobazam (JAN/USAN/INN); 1-Phenyl-5-methyl-8-chloro-1,2,4,5-tetrahydro-2,4-diketo-3H-1,5-benzodiazepine; 1-Phenyl-5-methyl-8-chloro-1,2,4,5-tetrahydro-2,4-dioxo-3H-1,5-benzodiazepine; 1-phenyl-5-methyl-8-chloro-1,2,4,5-tetrahydro-2,4-diketo-3H-1,5-benzodiazepine; 4(3H,5H)-dione; 7-Chloro-1-methyl-5-phenyl-1H-1,5-benzodiazepine-2; 7-Chloro-1-methyl-5-phenyl-1H-1,5-benzodiazepine-2,4(3H,5H)-dione; 7-Chloro-1-methyl-5-phenyl-1H-1,5-benzodiazepine-2,4-(3H,5H)-dione; 7-chloro-1-methyl-5-phenyl-1,5-benzodiazepine-2,4-dione
Drug Type
Small molecular drug
Indication Epilepsy; Anxiety disorder [ICD9: 300, 345; ICD10:F40-F42, G40] Approved [542156], [550702]
Therapeutic Class
Anticonvulsants
Company
Aventis Pharmaceuticals Inc.
Formula
C16H13ClN2O2
InChI
InChI=1S/C16H13ClN2O2/c1-18-13-8-7-11(17)9-14(13)19(16(21)10-15(18)20)12-5-3-2-4-6-12/h2-9H,10H2,1H3
InChIKey
CXOXHMZGEKVPMT-UHFFFAOYSA-N
CAS Number
CAS 22316-47-8
PubChem Compound ID
PubChem Substance ID
SuperDrug ATC ID
N05BA09
SuperDrug CAS ID
cas=022316478
Target and Pathway
Target(s) Gamma-aminobutyric acid receptor subunit alpha-1 Target Info Antagonist [536555]
KEGG Pathway Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
GABAergic synapse
Morphine addiction
Nicotine addiction
Reactome Ligand-gated ion channel transport
GABA A receptor activation
WikiPathways SIDS Susceptibility Pathways
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transport
References
Ref 542156(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7149).
Ref 550702Drug information of Clobazam, 2008. eduDrugs.
Ref 536555DrugBank: a knowledgebase for drugs, drug actions and drug targets. Nucleic Acids Res. 2008 Jan;36(Database issue):D901-6. Epub 2007 Nov 29.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.