Drug Information
Drug General Information | |||||
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Drug ID |
D0P2HR
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Former ID |
DIB018301
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Drug Name |
[3H]granisetron
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Synonyms |
[3H]-granisetron; [3H]-BRL-43694
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [539443] | ||
Structure |
Download2D MOL |
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Formula |
C18H24N4O
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InChI |
InChI=1S/C18H24N4O/c1-21-13-6-5-7-14(21)11-12(10-13)19-18(23)17-15-8-3-4-9-16(15)22(2)20-17/h3-4,8-9,12-14H,5-7,10-11H2,1-2H3,(H,19,23)
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InChIKey |
MFWNKCLOYSRHCJ-UHFFFAOYSA-N
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | 5-hydroxytryptamine receptor 3A | Target Info | Antagonist | [534215] | |
5-HT3AB | Target Info | Antagonist | [526116] | ||
KEGG Pathway | Serotonergic synapse | ||||
NetPath Pathway | IL2 Signaling Pathway | ||||
PANTHER Pathway | 5HT3 type receptor mediated signaling pathway | ||||
Reactome | Ligand-gated ion channel transport | ||||
WikiPathways | SIDS Susceptibility Pathways | ||||
Iron uptake and transport | |||||
References | |||||
Ref 526116 | Pharmacological comparison of human homomeric 5-HT3A receptors versus heteromeric 5-HT3A/3B receptors. Neuropharmacology. 2001 Aug;41(2):282-4. | ||||
Ref 534215 | Characterization of a human 5-hydroxytryptamine3 receptor type A (h5-HT3R-AS) subunit stably expressed in HEK 293 cells. Br J Pharmacol. 1996 Jul;118(5):1237-45. |
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