Drug Information
Drug General Information | |||||
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Drug ID |
D0Q7FM
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Former ID |
DNC004148
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Drug Name |
Azaperone
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [1] | ||
Structure |
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Download2D MOL |
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Formula |
C19H22FN3O
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Canonical SMILES |
C1CN(CCN1CCCC(=O)C2=CC=C(C=C2)F)C3=CC=CC=N3
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InChI |
1S/C19H22FN3O/c20-17-8-6-16(7-9-17)18(24)4-3-11-22-12-14-23(15-13-22)19-5-1-2-10-21-19/h1-2,5-10H,3-4,11-15H2
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InChIKey |
XTKDAFGWCDAMPY-UHFFFAOYSA-N
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CAS Number |
CAS 1649-18-9
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | D(3) dopamine receptor | Target Info | Inhibitor | [1] | |
D(2) dopamine receptor | Target Info | Inhibitor | [1] | ||
KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
Dopaminergic synapsehsa04015:Rap1 signaling pathway | |||||
cAMP signaling pathway | |||||
Gap junction | |||||
Dopaminergic synapse | |||||
Parkinson's disease | |||||
Cocaine addiction | |||||
Alcoholism | |||||
PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | |||||
Dopamine receptor mediated signaling pathway | |||||
Nicotine pharmacodynamics pathway | |||||
Reactome | Dopamine receptors | ||||
G alpha (i) signalling eventsR-HSA-390651:Dopamine receptors | |||||
G alpha (i) signalling events | |||||
WikiPathways | Monoamine GPCRs | ||||
GPCRs, Class A Rhodopsin-like | |||||
GPCR ligand binding | |||||
GPCR downstream signaling | |||||
Nicotine Activity on Dopaminergic Neurons | |||||
GPCRs, OtherWP666:Hypothetical Network for Drug Addiction | |||||
Genes and (Common) Pathways Underlying Drug Addiction | |||||
References | |||||
REF 1 | J Med Chem. 1993 Nov 26;36(24):3929-36.Evaluation of the effects of the enantiomers of reduced haloperidol, azaperol, and related 4-amino-1-arylbutanols on dopamine and sigma receptors. | ||||
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