| Drug General Information |
| Drug ID |
D0S6GK
|
| Former ID |
DNC003360
|
| Drug Name |
3,5-Difluorobenzenesulfonamide
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C6H5F2NO2S
|
| Canonical SMILES |
C1=C(C=C(C=C1F)S(=O)(=O)N)F
|
| InChI |
1S/C6H5F2NO2S/c7-4-1-5(8)3-6(2-4)12(9,10)11/h1-3H,(H2,9,10,11)
|
| InChIKey |
MKQPOVUFDWKPNO-UHFFFAOYSA-N
|
| PubChem Compound ID |
|
| PubChem Substance ID |
822665, 3215901, 6563736, 7887434, 10299863, 12107785, 24879622, 26697242, 29202650, 36888742, 46506239, 50312136, 87628557, 90342652, 104636156, 104696645, 117651878, 118509304, 125340759, 126643963, 126681916, 135591229, 136911676, 136987643, 137184181, 143460404, 143515394, 152244672, 160841873, 160965305, 162303126, 162762275, 163406914, 163784280, 163809890, 164799741, 165374865, 184554924, 202541381, 204403709, 206247233, 223495462, 223551723, 223658876, 224568647, 226905154, 241034647, 246946646, 249806533, 251888527
|
| Target and Pathway |
| Target(s) |
Carbonic anhydrase II |
Target Info |
Inhibitor |
[1]
|
|---|
|
KEGG Pathway
|
Nitrogen metabolism
|
|
Proximal tubule bicarbonate reclamation
|
|
Collecting duct acid secretion
|
|
Gastric acid secretion
|
|
Pancreatic secretion
|
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Bile secretion
|
|
NetPath Pathway
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IL4 Signaling Pathway
|
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EGFR1 Signaling Pathway
|
|
Reactome
|
Erythrocytes take up carbon dioxide and release oxygen
|
|
Erythrocytes take up oxygen and release carbon dioxide
|
|
Reversible hydration of carbon dioxide
|
|
WikiPathways
|
Reversible Hydration of Carbon Dioxide
|
|
Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes
|
|
Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes
|
| References |
| REF 1 | How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. |
|---|
