Drug Information

Drug General Information
Drug ID
D0T3VP
Former ID
DNC003489
Drug Name
4'-FLUORO-1,1'-BIPHENYL-4-CARBOXYLIC ACID
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551374]
Structure
Download
2D MOL

3D MOL
Formula
C13H9FO2
Canonical SMILES
C1=CC(=CC=C1C2=CC=C(C=C2)F)C(=O)O
InChI
1S/C13H9FO2/c14-12-7-5-10(6-8-12)9-1-3-11(4-2-9)13(15)16/h1-8H,(H,15,16)
InChIKey
LXWNTLBMNCXRQN-UHFFFAOYSA-N
PubChem Compound ID
2782689
PubChem Substance ID
3220290, 5146684, 6436251, 7885351, 8315245, 15838024, 24883857, 29196529, 39879058, 46393676, 57566384, 57686630, 79646603, 87360890, 92718343, 99443579, 103326999, 103956598, 104861624, 111410223, 117607592, 118289392, 124758051, 125092995, 125389179, 126580173, 126580174, 126621536, 126633220, 126653405, 126662782, 126725407, 126725890, 128557147, 131270945, 135719960, 136910531, 136991458, 137152845, 142530732, 144235532, 160781502, 160968193, 162140859, 162171321, 162266039, 162552426, 163393328, 163571259, 164209073
Target and Pathway
Target(s) Antiapoptotic protein BCL-XL Target Info Inhibitor [551374]
KEGG Pathway Ras signaling pathway
NF-kappa B signaling pathway
PI3K-Akt signaling pathway
Apoptosis
Jak-STAT signaling pathway
Amyotrophic lateral sclerosis (ALS)
Toxoplasmosis
HTLV-I infection
Pathways in cancer
Transcriptional misregulation in cancer
Pancreatic cancer
Chronic myeloid leukemia
Small cell lung cancer
NetPath Pathway IL2 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
Notch Signaling Pathway
PANTHER Pathway Apoptosis signaling pathway
CCKR signaling map ST
Pathway Interaction Database IL2 signaling events mediated by PI3K
IL3-mediated signaling events
Caspase Cascade in Apoptosis
EPO signaling pathway
IL2 signaling events mediated by STAT5
Reactome BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members
The NLRP1 inflammasome
WikiPathways IL-6 signaling pathway
IL-3 Signaling Pathway
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
Apoptosis
Amyotrophic lateral sclerosis (ALS)
TNF alpha Signaling Pathway
IL-7 Signaling Pathway
Leptin signaling pathway
Intrinsic Pathway for Apoptosis
Apoptosis Modulation and Signaling
References
Ref 551374The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
Ref 551374The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.

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